Control of mandibular gland pheromone synthesis by alternative splicing of the CP-2 transcription factor gemini in honeybees (Apis mellifera carnica)
العنوان: | Control of mandibular gland pheromone synthesis by alternative splicing of the CP-2 transcription factor gemini in honeybees (Apis mellifera carnica) |
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المؤلفون: | Abdullahi Ahmed Yusuf, Robin M. Crewe, Christian Walter Werner Pirk, Robin F. A. Moritz, Antje Jarosch-Perlow |
المصدر: | Apidologie Apidologie, 2018, 49 (4), pp.450-458. ⟨10.1007/s13592-018-0571-5⟩ |
بيانات النشر: | HAL CCSD, 2018. |
سنة النشر: | 2018 |
مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, reproductive dominance, [SDV]Life Sciences [q-bio], Pheromone synthesis, Ovary, Biology, 010603 evolutionary biology, 01 natural sciences, 03 medical and health sciences, pheromone, RNA interference, stomatognathic system, medicine, worker reproduction, Transcription factor, Regulator gene, Alternative splicing, ovary activation, 3. Good health, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Insect Science, Sex pheromone, Pheromone |
الوصف: | International audience; AbstractThe honeybee queen’s mandibular gland pheromones (QMP) are essential for the suppression of worker reproduction. Worker ovary activation is regulated by alternative splicing of a CP2-transcription factor named gemini. Since workers with activated ovaries also produce QMP in their mandibular glands, we tested whether alternative splicing of gemini also controls mandibular gland pheromone biosynthesis in workers using RNA interference. Altering the splice pattern of gemini resulted in enhanced levels of the queen-specific components of the mandibular gland pheromone in queenless honeybee workers, suggesting that gemini functions as a pleiotropic regulatory switch influencing both ovary activation and resulting in QMP synthesis in workers. Because the QMP produced by these workers suppresses ovary activation in other workers, gemini seems to be a key regulatory gene affecting reproductive hierarchies among workers in queenless colonies. |
اللغة: | English |
تدمد: | 0044-8435 |
DOI: | 10.1007/s13592-018-0571-5⟩ |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87cfa5f10423e16d0f2f4674e73835d https://hal.archives-ouvertes.fr/hal-02973371 |
Rights: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....e87cfa5f10423e16d0f2f4674e73835d |
قاعدة البيانات: | OpenAIRE |
تدمد: | 00448435 |
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DOI: | 10.1007/s13592-018-0571-5⟩ |