Severe retinopathy of prematurity and visual outcomes in British Columbia: a 10-year analysis
| العنوان: | Severe retinopathy of prematurity and visual outcomes in British Columbia: a 10-year analysis |
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| المؤلفون: | C Matsuba, Anne Synnes, Verónica Schiariti, Jill S Houbé |
| المصدر: | Journal of Perinatology. 28:566-572 |
| بيانات النشر: | Springer Science and Business Media LLC, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Pediatrics, medicine.medical_specialty, genetic structures, MEDLINE, macromolecular substances, Blindness, Laser therapy, Intensive Care Units, Neonatal, medicine, Humans, Infant, Very Low Birth Weight, Retinopathy of Prematurity, Child, Retrospective Studies, British Columbia, business.industry, Incidence, musculoskeletal, neural, and ocular physiology, Incidence (epidemiology), Infant, Newborn, Obstetrics and Gynecology, Retrospective cohort study, Retinopathy of prematurity, Hospitals, Pediatric, Refractive Errors, medicine.disease, Infant newborn, eye diseases, nervous system, Infant, Extremely Low Birth Weight, Child, Preschool, Pediatrics, Perinatology and Child Health, Laser Therapy, business, Infant, Premature |
| الوصف: | To describe the incidence trend and long-term visual outcomes of infants diagnosed with stages 3 to 4 retinopathy of prematurity (ROP) or laser-treated ROP born in British Columbia (Canada).Data from all (n=1384) neonates with birth weight (BW)1250 g, admitted to British Columbia Children's Hospital between period 1 (January 1992 to December 1996) and period 2 (January 1997 to December 2001) were analyzed. Ophthalmologic records of infants with stages 3 to 4 ROP or laser-treated ROP were abstracted. chi(2)- and t-test were used to compare neonatal characteristics between periods. Logistic regression was used to identify risk factors associated with visual impairment (defined as visual acuityor=20/60 or visual field restriction of 20 degrees binocularly).Of 1159 surviving infants, 887 were examined for acute ROP (473 in period 1, 414 in period 2). Stages 3 to 4 ROP or laser-treated ROP were present in 35 infants in period 1 (7%) and 59 in period 2 (14%), Por=0001. Infants born in period 2 had lower mean BW and gestational age. Among infants who developed severe ROP or laser-treated ROP, binocular visual impairment was present in eight children in period 1 and seven in period 2. Refractive errors, including myopia and astigmatism, were increased in period 2. Children who developed periventricular leucomalacia had the highest risk of visual impairment at 4 to 6 years of age.During the 10-year study period, a significant increase in rates of stages 3 to 4 or laser-treated ROP was not associated with increases in visual impairment rates. |
| تدمد: | 1476-5543 0743-8346 |
| DOI: | 10.1038/jp.2008.34 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e083b8166446a165f676675febe050 https://doi.org/10.1038/jp.2008.34 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e7e083b8166446a165f676675febe050 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14765543 07438346 |
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| DOI: | 10.1038/jp.2008.34 |