GANGLIOSIDES IN DNA VIRUS-TRANSFORMED AND SPONTANEOUSLY TRANSFORMED TUMORIGENIC MOUSE CELL LINES
| العنوان: | GANGLIOSIDES IN DNA VIRUS-TRANSFORMED AND SPONTANEOUSLY TRANSFORMED TUMORIGENIC MOUSE CELL LINES |
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| المؤلفون: | Roscoe O. Brady, Vivian W. McFarland, Roy M. Bradley, Peter T. Mora |
| المصدر: | Proceedings of the National Academy of Sciences. 63:1290-1296 |
| بيانات النشر: | Proceedings of the National Academy of Sciences, 1969. |
| سنة النشر: | 1969 |
| مصطلحات موضوعية: | viruses, Simian virus 40, Virus, Cell Line, Mice, Tissue culture, Glycolipid, Culture Techniques, Gangliosides, medicine, Animals, Neoplasm, Multidisciplinary, Ganglioside, biology, DNA virus, medicine.disease, biology.organism_classification, Molecular biology, Cell Transformation, Neoplastic, Rickettsia, Cell culture, sense organs, Chromatography, Thin Layer, Biological Sciences: Biochemistry, Glycolipids |
| الوصف: | In mouse cell lines transformed by SV40 virus, a decrease was observed in the higher ganglioside homologues disialo-ceramidetetrahexoside and monosialo-ceramidetetrahexoside. Such change was observed only in cells which carry the virus genome, and it correlated with increased saturation density in tissue culture and with rejection in immunologically competent syngeneic host. This indicates that the change is one of the virus-regulated functions, and it is postulated that it relates to the rejection of the virus-transformed cells. |
| تدمد: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.63.4.1290 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76879810eadab1fdf036afb1ba35c63 https://doi.org/10.1073/pnas.63.4.1290 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e76879810eadab1fdf036afb1ba35c63 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10916490 00278424 |
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| DOI: | 10.1073/pnas.63.4.1290 |