Outcomes of Kidney Transplant Recipients With Percutaneous Ureteral Interventions: A Single-Center Study

التفاصيل البيبلوغرافية
العنوان: Outcomes of Kidney Transplant Recipients With Percutaneous Ureteral Interventions: A Single-Center Study
المؤلفون: Randall S. Sung, Chrystina James, John T. Stoffel, Dushyanth Srinivasan, Kori Bradley
المصدر: Transplantation Direct
بيانات النشر: Ovid Technologies (Wolters Kluwer Health), 2017.
سنة النشر: 2017
مصطلحات موضوعية: Transplantation, medicine.medical_specialty, Percutaneous, urogenital system, business.industry, Hazard ratio, 030232 urology & nephrology, urologic and male genital diseases, medicine.disease, Single Center, Kidney Transplantation, female genital diseases and pregnancy complications, 030218 nuclear medicine & medical imaging, Surgery, 03 medical and health sciences, surgical procedures, operative, 0302 clinical medicine, medicine, Balloon dilation, Ureteral Stricture, Complication, business, Kidney transplantation, Survival analysis
الوصف: Background Long-term outcomes of kidney transplantation recipients with percutaneous ureteral management of transplant ureteral complications are not well characterized. Methods Electronic records of 1753 recipients of kidney-alone transplant between January 2000 and December 2008 were reviewed. One hundred thirty-one patients were identified to have undergone percutaneous ureteral management, with placement of percutaneous nephrostomy tube or additional intervention (nephroureteral stenting and/or balloon dilation). Indications for intervention included transplant ureteral stricture or ureteral leak. Kaplan-Meier survival curves and multivariable regression modeling were performed to determine survival outcomes. Results Kaplan- Meier graft survival (P = 0.04) was lower in patients with percutaneous ureteral intervention for transplant ureteral complication. Graft survival at 1, 5, and 10 years was 94.3% 78.3%, and 59.1% for no intervention and 97.2%, 72.1%, and 36.2% for intervention cohort. Patient survival (P = 0.69) was similar between cohorts. Multivariate analysis demonstrated no association with graft failure (hazard ratio, 1.21; 95% confidence interval, 0.67-2.19; P = 0.53) or patient death (hazard ratio, 0.56; 95% confidence interval, 0.22-1.41; P = 0.22) in intervention group. The major cause of graft failure was infection for percutaneous ureteral intervention group (20.4%) and chronic rejection for those without intervention (17.3%). Conclusions Kidney transplant recipients with percutaneous ureteral interventions for ureteral complications do not have a significant difference in graft and patient survival outcomes. Therefore, aggressive nonoperative management can be confidently pursued in the appropriate clinical setting.
تدمد: 2373-8731
DOI: 10.1097/txd.0000000000000637
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5bcaa18cec894a95c294056b85e13f7
https://doi.org/10.1097/txd.0000000000000637
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....e5bcaa18cec894a95c294056b85e13f7
قاعدة البيانات: OpenAIRE
الوصف
تدمد:23738731
DOI:10.1097/txd.0000000000000637