Atherosclerosis in Patients With Cyanotic Congenital Heart Disease
| العنوان: | Atherosclerosis in Patients With Cyanotic Congenital Heart Disease |
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| المؤلفون: | Johan Gort, Aeiko H. Zwinderman, Luciano Daliento, Arie P.J. van Dijk, Rudolphus Berger, Karlijn M. Mulder, Erik de Groot, Marielle G. J. Duffels, Mieke D. Trip, Barbara J.M. Mulder, Elke S. Hoendermis |
| المساهمون: | Cardiology, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine, APH - Amsterdam Public Health, Epidemiology and Data Science, Faculteit der Geneeskunde, Faculteit Medische Wetenschappen/UMCG, Cardiovascular Centre (CVC), Vascular Ageing Programme (VAP) |
| المصدر: | Circulation journal, 74(7), 1436-1441. Japanese Circulation Society Circulation journal, 74(7), 1436-1441 Circulation Journal, 74, 1436-41 Circulation Journal, 74, 7, pp. 1436-41 |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Blood Platelets, Male, medicine.medical_specialty, PULMONARY ARTERIAL-HYPERTENSION, Adolescent, Heart Diseases, Heart disease, Bilirubin, Diastole, Blood Pressure, ERYTHROCYTOSIS, INTIMA-MEDIA THICKNESS, chemistry.chemical_compound, Risk Factors, Internal medicine, YOUNG-ADULTS, medicine, WALL THICKNESS, MANAGEMENT, Humans, cardiovascular diseases, Carotid intima-media thickness, Cyanotic congenital heart disease, Cyanosis, Cardiovascular diseases [NCEBP 14], business.industry, Cholesterol, CARDIOVASCULAR RISK, P-SELECTIN, CHOLESTEROL, Case-control study, THROMBOMODULIN, Eisenmenger syndrome, General Medicine, Middle Aged, medicine.disease, Atherosclerosis, Blood pressure, chemistry, Intima-media thickness, Case-Control Studies, Cardiology, Female, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Contains fulltext : 88391.pdf (Publisher’s version ) (Open Access) BACKGROUND: Cyanotic patients with congenital heart disease (CHD) might be protected against atherosclerosis. METHODS AND RESULTS: Atherosclerotic risk factors and carotid intima - media thickness (IMT) were investigated in adults with cyanotic CHD and in unaffected age- and sex-matched controls. Fifty-four cyanotic patients (30 men, mean age 38, range 19-60 years) and 54 controls were included. Mean transcutaneous saturation of the cyanotic patients was 81+/-6%. Mean carotid IMT adjusted for age was significantly decreased in cyanotic patients compared to controls (0.55+/-0.1 mm vs 0.58+/-0.08 mm: DeltaIMT =0.04 mm [SE 0.015], P=0.01). In cyanotic patients lower total cholesterol levels were observed (4.4+/-1 mmol/L vs 4.9+/-1 mmol/L; P=0.02), as well as lower thrombocyte levels (173+/-81 x 10(9) /L vs 255+/-54 x 10(9) /L; P |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1346-9843 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a48b78688c90b86d6a309afe08706a https://pure.amc.nl/en/publications/atherosclerosis-in-patients-with-cyanotic-congenital-heart-disease(f8df01dc-4013-48c5-8e18-d0a848a4beec).html |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e4a48b78688c90b86d6a309afe08706a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13469843 |
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