Identification of New Compounds from Sage Flowers (Salvia officinalis L.) as Markers for Quality Control and the Influence of the Manufacturing Technology on the Chemical Composition and Antibacterial Activity of Sage Flower Extracts
| العنوان: | Identification of New Compounds from Sage Flowers (Salvia officinalis L.) as Markers for Quality Control and the Influence of the Manufacturing Technology on the Chemical Composition and Antibacterial Activity of Sage Flower Extracts |
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| المؤلفون: | Martin Kaiser, Tilo Lübken, Diana Wolf, Sebastian Gericke, Karl Speer, Christian Hannig |
| المصدر: | Journal of Agricultural and Food Chemistry. 66:1843-1853 |
| بيانات النشر: | American Chemical Society (ACS), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Quality Control, 0301 basic medicine, food.ingredient, Lavandula, Flowers, Chemical Fractionation, Salvia, 01 natural sciences, High-performance liquid chromatography, Mass Spectrometry, Carnosol, 03 medical and health sciences, chemistry.chemical_compound, food, X-Ray Diffraction, Salvia officinalis, Chromatography, High Pressure Liquid, biology, Traditional medicine, Plant Extracts, 010405 organic chemistry, SAGE, food and beverages, General Chemistry, biology.organism_classification, food.food, Anti-Bacterial Agents, 0104 chemical sciences, 030104 developmental biology, chemistry, Herb, General Agricultural and Biological Sciences, Antibacterial activity |
| الوصف: | Parts of Salvia species such as its flowers and leaves are currently used as a culinary herb and for some medicinal applications. To distinguish the different sage extracts it is necessary to analyze their individual chemical compositions. Their characteristic compounds might be established as markers to differentiate between sage flowers and leaf extracts or to determine the manufacturing technology and storage conditions. Tri-p-coumaroylspermidine can be detected only in flowers and has been described here for Salvia and Lavandula species for the first time. Markers for oxidation processes are the novel compounds salviquinone A and B, which were generated from carnosol by exposure to oxygen. Caffeic acid ethyl ester was established as an indirect marker for the usage of ethanol as extraction solvent. The compounds were identified by LC-QTOF-HRESIMS, LC-MS, NMR, IR, and single-crystal X-ray diffraction after isolation by semipreparative HPLC. Furthermore, sage flower resin showed interesting antibacterial in vitro activities against Gram-positive and Gram-negative bacteria. |
| تدمد: | 1520-5118 0021-8561 |
| DOI: | 10.1021/acs.jafc.8b00581 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bb00f6abb5be09506068ae2332d735 https://doi.org/10.1021/acs.jafc.8b00581 |
| رقم الانضمام: | edsair.doi.dedup.....e2bb00f6abb5be09506068ae2332d735 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15205118 00218561 |
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| DOI: | 10.1021/acs.jafc.8b00581 |