Endometriosis, Psoriasis, and Psoriatic Arthritis: A Prospective Cohort Study
| العنوان: | Endometriosis, Psoriasis, and Psoriatic Arthritis: A Prospective Cohort Study |
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| المؤلفون: | Harris, Holly R, Korkes, Karen Moreno Nascimento, Li, Tricia, Kvaskoff, Marina, Cho, Eunyoung, Carvalho, Luiz Fernando, Qureshi, Abrar A, Abrao, Mauricio, Missmer, Stacey A |
| المصدر: | Am J Epidemiol |
| بيانات النشر: | Oxford University Press (OUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Cohort Studies, Risk Factors, Epidemiology, Arthritis, Psoriatic, Endometriosis, Humans, Psoriasis, Female, Original Contribution, Prospective Studies, United States |
| الوصف: | Endometriosis, psoriasis, and psoriatic arthritis (PsA) are chronic inflammatory disorders whose etiologies remain poorly understood but may be correlated, as endometriosis has been associated with other inflammatory disorders. We investigated the bidirectional associations between laparoscopically confirmed endometriosis and physician-diagnosed psoriasis and PsA in the Nurses’ Health Study II cohort (n = 116,429, United States, 1991–2013). We confirmed 4,112 incident cases of laparoscopically confirmed endometriosis (mean age at diagnosis = 40.3 years) and 697 validated physician-diagnosed cases of psoriasis (mean age at diagnosis = 43.6 years), 110 of which presented with concomitant PsA. A history of psoriasis with concomitant PsA was associated with a 2-fold higher risk of endometriosis (hazard ratio (HR) = 2.01, 95% CI: 1.23, 3.30); however, no association was observed between psoriasis without PsA and endometriosis risk (HR = 0.93, 95% CI: 0.68, 1.26). When endometriosis was the exposure, it was not associated with a risk of subsequent psoriasis (HR = 1.28, 95% CI: 0.95, 1.72). The risk of psoriasis with PsA was notably higher; however, the sample size was small and the confidence intervals wide (HR = 1.77, 95% CI: 0.89, 3.52). Our findings suggest that psoriasis with concomitant PsA is associated with greater risk of laparoscopically confirmed endometriosis. In addition, there was a suggestive association between endometriosis diagnosis and subsequent risk of psoriasis with PsA. |
| تدمد: | 1476-6256 0002-9262 |
| DOI: | 10.1093/aje/kwac009 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e118e80a56e89178a48ca0b42872cf59 https://doi.org/10.1093/aje/kwac009 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e118e80a56e89178a48ca0b42872cf59 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14766256 00029262 |
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| DOI: | 10.1093/aje/kwac009 |