The Strain Response to Intraocular Pressure Decrease in the Lamina Cribrosa of Patients with Glaucoma
العنوان: | The Strain Response to Intraocular Pressure Decrease in the Lamina Cribrosa of Patients with Glaucoma |
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المؤلفون: | Cameron A. Czerpak, Michael Saheb Kashaf, Brandon K. Zimmerman, Harry A. Quigley, Thao D. Nguyen |
المصدر: | Ophthalmology Glaucoma. 6:11-22 |
بيانات النشر: | Elsevier BV, 2023. |
سنة النشر: | 2023 |
مصطلحات موضوعية: | General Medicine |
الوصف: | To measure biomechanical strains in the lamina cribrosa (LC) of living human eyes with intraocular pressure (IOP) lowering.Cohort study.Patients with glaucoma underwent imaging before and after laser suturelysis after trabeculectomy surgery (29 image pairs; 26 persons).Noninvasive imaging of the eye.Strains in optic nerve head tissue and changes in depths of the anterior border of the LC.Intraocular pressure decreases caused the LC to expand in thickness in the anterior-posterior strain (EWith IOP lowering, the LC moves either into or out of the eye but, on average, expands in thickness and contracts in radius. Shear strains are nearly as substantial as in-plane strains. Biomechanical strains are more compliant in eyes with greater glaucoma damage. This work was registered at ClinicalTrials.gov as NCT03267849. |
تدمد: | 2589-4196 0326-7849 |
DOI: | 10.1016/j.ogla.2022.07.005 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d191ab2c3dde6f69d22ccbb8527645 https://doi.org/10.1016/j.ogla.2022.07.005 |
Rights: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....e0d191ab2c3dde6f69d22ccbb8527645 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 25894196 03267849 |
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DOI: | 10.1016/j.ogla.2022.07.005 |