[3 + 2]-Annulation of Azaoxyallyl Cations and Thiocarbonyls for the Assembly of Thiazolidin-4-ones
| العنوان: | [3 + 2]-Annulation of Azaoxyallyl Cations and Thiocarbonyls for the Assembly of Thiazolidin-4-ones |
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| المؤلفون: | Jaideep Saha, Vandana Jaiswal, Dinabandhu Das, Kuldeep Singh, Biplab Mondal |
| المصدر: | Organic Letters. 21:5848-5852 |
| بيانات النشر: | American Chemical Society (ACS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Annulation, chemistry.chemical_compound, 010405 organic chemistry, Chemistry, Organic Chemistry, Functional group, Lewis acids and bases, Physical and Theoretical Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences |
| الوصف: | A base-promoted, efficient [3 + 2] annulation between azaoxyallyl cations and thiocarbonyls is reported for flexible access to highly functionalized thiazolidin-4-one derivatives in good to excellent yields. An intriguing feature of this method is the metal or Lewis acid free late-stage entry of distinct set of functional groups at C2 of thiazolidin-4-ones via substitution of a latent amino functional group. Overall, this approach constitutes a general platform for convenient access to this medicinally important scaffold. |
| تدمد: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.9b01933 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc4ca39ed79e865b4be8d325cc31c85 https://doi.org/10.1021/acs.orglett.9b01933 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....dcc4ca39ed79e865b4be8d325cc31c85 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15237052 15237060 |
|---|---|
| DOI: | 10.1021/acs.orglett.9b01933 |