Is DWI/ADC a Useful Tool in the Characterization of Focal Hepatic Lesions Suspected of Malignancy?
| العنوان: | Is DWI/ADC a Useful Tool in the Characterization of Focal Hepatic Lesions Suspected of Malignancy? |
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| المؤلفون: | Letícia Silva Sene, Janio Szklaruk, Maria Luiza Testa, Marcos Duarte Guimarães, Aline Santos Damascena, Edson Marchiori, Rubens Chojniak |
| المصدر: | PLoS ONE PLoS ONE, Vol 9, Iss 7, p e101944 (2014) |
| بيانات النشر: | Public Library of Science, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, lcsh:Medicine, Gastroenterology and Hepatology, Malignancy, Metastasis, Diagnostic Radiology, Lesion, Diagnosis, Differential, Young Adult, Diagnostic Medicine, Basic Cancer Research, Medicine and Health Sciences, Medicine, Effective diffusion coefficient, Humans, Prospective Studies, Prospective cohort study, lcsh:Science, Aged, Aged, 80 and over, Multidisciplinary, medicine.diagnostic_test, business.industry, Echo-Planar Imaging, Liver Diseases, Radiology and Imaging, lcsh:R, Liver Neoplasms, Cancer, Cancers and Neoplasms, Magnetic resonance imaging, Middle Aged, medicine.disease, Magnetic Resonance Imaging, body regions, Diffusion Magnetic Resonance Imaging, Oncology, ROC Curve, lcsh:Q, Female, Radiology, Differential diagnosis, medicine.symptom, business, Research Article |
| الوصف: | OBJECTIVE: Apparent diffusion coefficient (ADC) values calculated through magnetic resonance imaging have been proposed as a useful tool to distinguish benign from malignant liver lesions. Most studies however included simple cysts in their analysis. Liver cysts are easy to diagnose, have very high ADC values and their inclusion facilitates differentiation in the ADC values between benign and malignant liver lesions groups. We prospectively evaluated the ability of ADC values to differentiate metastatic liver lesions from all benign or only solid benign liver lesions. MATERIAL AND METHODS: Sixty-seven adult cancer patients with 188 liver lesions were evaluated. Lesions were categorized as metastatic or benign throughout imaging and clinical evaluation. One hundred and five (105) metastatic lesions and 83 benign lesions including hemangiomas (37), cysts (42), adenomas (2) and focal nodular hyperplasias (2) were evaluated. ADC values were calculated for each lesion utilizing two b values (0 and 600 sec/mm2). RESULTS: The average ADC value for cysts was 2.4×10(-3) mm2/sec (CI: 2.1-2.6), for solid benign lesions was 1.4×10(-3) mm2/sec (CI: 1.1-1.7) and for metastases was 1.0×10(-3) mm2/sec (CI: 0.8-1.3). There was a difference between the ADC values of metastases and benign solid lesions (p |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe2dbe32748effc5ef0a5492c8f4565 http://europepmc.org/articles/PMC4099077 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....dbe2dbe32748effc5ef0a5492c8f4565 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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