Automated Detection of Malaria-Associated Pseudoeosinophilia and Abnormal WBC Scattergram by the Sysmex XE-2100 Hematology Analyzer: A Clinical Study with 1,801 Patients and Real-Time Quantitative PCR Analysis in Vivax Malaria-Endemic Area
| العنوان: | Automated Detection of Malaria-Associated Pseudoeosinophilia and Abnormal WBC Scattergram by the Sysmex XE-2100 Hematology Analyzer: A Clinical Study with 1,801 Patients and Real-Time Quantitative PCR Analysis in Vivax Malaria-Endemic Area |
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| المؤلفون: | Young Kyu Sun, Jong Ha Yoo, Jong Rak Choi, Jaewoo Song, Tae Sung Park, Kyung A. Lee, Young Ah Kim |
| المصدر: | The American Journal of Tropical Medicine and Hygiene. 82:412-414 |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | medicine.medical_specialty, Pathology, Endemic Diseases, Parasitemia, Biology, Polymerase Chain Reaction, Sensitivity and Specificity, Automation, Leukocyte Count, Hematology analyzer, Virology, Internal medicine, White blood cell, Eosinophilia, parasitic diseases, Malaria, Vivax, medicine, Humans, Hematologic Tests, Sysmex XE-2100, Hematology, Articles, medicine.disease, Abnormal wbc, Malaria, Infectious Diseases, medicine.anatomical_structure, Vivax malaria, Parasitology |
| الوصف: | Recently, the XE-2100 hematology analyzer was investigated in a rather small patient group; pseudoeosinophilia or abnormal white blood cell (WBC) scattergrams reported by this instrument were considered as significantly valuable diagnostic parameters in detecting vivax malaria. This study was conducted not only to assess the usefulness of pseudoeosinophilia or abnormal WBC scattergram in vivax malaria-endemic areas with large patient groups (N = 1,801) but also to investigate the correlation of parasitemia and platelet count with pseudoeosinophilia and abnormal WBC scattergrams. Of the 1,801 analyzed patients, 413 (22.9%) were found to have malaria by Wright–Giemsa stained blood smears. Overall, either pseudoeosinophilia or abnormal WBC scattergram was detected in 191 of 413 malaria patients and 4 of 1,388 patients without malaria (sensitivity = 46.2%, specificity = 99.7%). We suggest that clinical hematology laboratories using the XE-2100 analyzer should be aware of such specific parameters, even with the absence of a clinical request. |
| تدمد: | 1476-1645 0002-9637 |
| DOI: | 10.4269/ajtmh.2010.09-0560 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa2cf85c8cf8ef5f9e212b1253a9690 https://doi.org/10.4269/ajtmh.2010.09-0560 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....daa2cf85c8cf8ef5f9e212b1253a9690 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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| DOI: | 10.4269/ajtmh.2010.09-0560 |