Chiral profiling of azole antifungals in municipal wastewater and recipient rivers of the Pearl River Delta, China
| العنوان: | Chiral profiling of azole antifungals in municipal wastewater and recipient rivers of the Pearl River Delta, China |
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| المؤلفون: | Zhifang Wang, Chunwei Wang, Xianzhi Peng, Qiuxin Huang |
| المصدر: | Environmental Science and Pollution Research. 20:8890-8899 |
| بيانات النشر: | Springer Science and Business Media LLC, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | China, Antifungal Agents, Econazole, Health, Toxicology and Mutagenesis, Sewage, Wastewater, chemistry.chemical_compound, Rivers, medicine, Environmental Chemistry, Imidazole, Tebuconazole, chemistry.chemical_classification, Chromatography, business.industry, Imidazoles, General Medicine, Pollution, chemistry, Environmental chemistry, Azole, Sewage treatment, Enantiomer, business, Water Pollutants, Chemical, Environmental Monitoring, medicine.drug |
| الوصف: | Enantiomeric compositions and fractions (EFs) of three chiral imidazole (econazole, ketoconazole, and miconazole) and one chiral triazole (tebuconazole) antifungals were investigated in wastewater, river water, and bed sediment of the Pearl River Delta, South China. The imidazole pharmaceuticals in the untreated wastewater were racemic to weakly nonracemic (EFs of 0.450-0.530) and showed weak enantioselectivity during treatment in the sewage treatment plant. The EFs of the dissolved azole antifungals were usually different from those of the sorbed azoles in the suspended particulate matter, suggesting different behaviors for the enantiomers of the chiral azole antifungals in the dissolved and particulate phases of the wastewater. The azole antifungals were widely present in the rivers. The bed sediment was a sink for the imidazole antifungals. The imidazoles were prevalently racemic, whereas tebuconazole was widely nonracemic in the rivers. Seasonal effects were observed on distribution and chirality of the azole antifungals. Concentrations of the azole antifungals in the river water were relatively higher in winter than in spring and summer while the EF of miconazole in the river water was higher in summer. The mechanism of enantiomeric behavior of the chiral azole antifungals in the environment warrants further research. |
| تدمد: | 1614-7499 0944-1344 |
| DOI: | 10.1007/s11356-013-1862-z |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da18768fad06fcf80e8bb976431c79d0 https://doi.org/10.1007/s11356-013-1862-z |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....da18768fad06fcf80e8bb976431c79d0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16147499 09441344 |
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| DOI: | 10.1007/s11356-013-1862-z |