التفاصيل البيبلوغرافية
| العنوان: |
Decomposing the mutational landscape of cancer genomes with RepairSig |
| المؤلفون: |
Sara Bernardo, Mathilde Meyenberg, Joanna I. Loizou |
| المصدر: |
Cell Systems |
| مصطلحات موضوعية: |
Histology, DNA Repair, DNA repair, DNA damage, Cell, Computational biology, Biology, medicine.disease_cause, Genome, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Humans, 030304 developmental biology, 0303 health sciences, Genome, Human, DNA replication, Cancer, Cell Biology, medicine.disease, medicine.anatomical_structure, Mutation, Carcinogenesis, 030217 neurology & neurosurgery, DNA Damage |
| الوصف: |
Mutational signatures are the outcomes of mutagenic processes that occur prior to, and during, tumorigenesis as a result of DNA damage, DNA repair, and DNA replication. In this issue of Cell Systems, Wojtowicz et al. introduce a new computational model aimed at deconstructing the mutational processes that shape cancer genomes. |
| اللغة: |
English |
| تدمد: |
2405-4712 |
| DOI: |
10.1016/j.cels.2021.09.009 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d972b1c18d3225828f0375c67a7fde56 |
| Rights: |
CLOSED |
| رقم الانضمام: |
edsair.doi.dedup.....d972b1c18d3225828f0375c67a7fde56 |
| قاعدة البيانات: |
OpenAIRE |