Downregulation of PPP2R5E is a common event in acute myeloid leukemia that affects the oncogenic potential of leukemic cells

التفاصيل البيبلوغرافية
العنوان: Downregulation of PPP2R5E is a common event in acute myeloid leukemia that affects the oncogenic potential of leukemic cells
المؤلفون: Laura Garcia-Orti, Remedios Castello-Cros, Cristina Cirauqui, Ion Cristóbal, María José Calasanz, María D. Odero
بيانات النشر: Ferrata Storti Foundation, 2013.
سنة النشر: 2013
مصطلحات موضوعية: Kinase, Phosphatase, RUNX1T1, Myeloid leukemia, Down-Regulation, HL-60 Cells, Hematology, Protein phosphatase 2, Biology, PTPN11, Leukemia, Myeloid, Acute, Downregulation and upregulation, Online-Only Articles, hemic and lymphatic diseases, Cell Line, Tumor, Cancer research, Humans, Protein Phosphatase 2, Protein kinase B
الوصف: Genetic aberrations affecting kinases have been widely studied in acute myeloid leukemia (AML). However, the role of phosphatases remains underexplored. Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase that participates in many signaling pathways.[1][1] Transformed cells present
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78e1c2becd0d724e16b106532b3a4cc
https://europepmc.org/articles/PMC3762109/
Rights: OPEN
رقم الانضمام: edsair.doi.dedup.....d78e1c2becd0d724e16b106532b3a4cc
قاعدة البيانات: OpenAIRE