Relationship between calcitrophic hormones and blood pressure in elderly subjects

التفاصيل البيبلوغرافية
العنوان: Relationship between calcitrophic hormones and blood pressure in elderly subjects
المؤلفون: Richard L. Prince, T. Welborn, R.W. Retallack, A. St John, K. Hoad, I. Dick
المصدر: European Journal of Endocrinology. 130:446-450
بيانات النشر: Oxford University Press (OUP), 1994.
سنة النشر: 1994
مصطلحات موضوعية: Male, medicine.medical_specialty, Calcitriol, Endocrinology, Diabetes and Metabolism, Parathyroid hormone, Blood Pressure, Body Mass Index, Phosphates, Endocrinology, Internal medicine, medicine, Humans, Serum Albumin, Aged, Analysis of Variance, business.industry, Age Factors, Albumin, General Medicine, Mean blood pressure, Blood pressure, Parathyroid Hormone, Calcitonin, Creatinine, Hypertension, Regression Analysis, Calcium, Female, business, Body mass index, medicine.drug, Hormone
الوصف: St John A, Dick I, Hoad K, Retallack R, Welborn T, Prince R. Relationship between calcitrophic hormones and blood pressure in elderly subjects. Eur J Endocrinol 1994;130:446–50. ISSN 0804–4643 The relationship between calcitrophic hormones and blood pressure has been investigated in 583 elderly subjects who were untreated for hypertension. Univariate analysis demonstrated that serum parathyroid hormone, calcitriol, albumin and calcium were correlated significantly with mean blood pressure (r = +0.15, +0.10, +0.14 and +0.11, respectively), as were body mass index and age (r = +0.19 and +0.10, respectively). Parathyroid hormone also was correlated positively with both age and calcitriol (r = +0.34 and +0.15, respectively) and negatively with plasma calcium and albumin (r = −0.09 and −0.09, respectively). Multivariate analysis demonstrated that when allowing for age and body mass index, parathyroid hormone and calcitriol were both significant independent determinants of the mean blood pressure. When other independent variables were included in the analysis, parathyroid hormone but not calcitriol remained a significant predictor of mean blood pressure. This study has demonstrated a weak but significant relationship between blood pressure and calcitrophic hormones in a group of elderly people. The data are consistent with the hypothesis that hypertension may be due in part to calcium deficiency. Andrew St John, Department of Biochemistry, Royal Perth Hospital, GPO Box X2213, Perth, Western Australia
تدمد: 1479-683X
0804-4643
DOI: 10.1530/eje.0.1300446
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e92ad4f0829d875edc3512cc83cb60
https://doi.org/10.1530/eje.0.1300446
رقم الانضمام: edsair.doi.dedup.....d4e92ad4f0829d875edc3512cc83cb60
قاعدة البيانات: OpenAIRE
الوصف
تدمد:1479683X
08044643
DOI:10.1530/eje.0.1300446