Evolution of self-perceived swallowing function, tongue strength and swallow-related quality of life during radiotherapy in head and neck cancer patients
| العنوان: | Evolution of self-perceived swallowing function, tongue strength and swallow-related quality of life during radiotherapy in head and neck cancer patients |
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| المؤلفون: | Cathy L. Lazarus, Sophie Cvilic, Paul Van de Heyning, Diane Van Rompaey, Steven Mariën, Carl Van Laer, Pol Specenier, Johan Allouche, Leen Van den Steen, Laurence Delacroix, Jan B. Vermorken, Jan Vanderwegen, Tatiana Dragan, Gilbert Chantrain, Jean-François Daisne, Georges Lawson, Marc De Bodt, Dirk Van Gestel, S. Beauvois, Olivier M. Vanderveken, Danielle Van den Weyngaert, Gwen Van Nuffelen, Marc Peeters, Gauthier Desuter |
| المساهمون: | UCL - (MGD) Service d'oto-rhino-laryngologie, UCL - SSS/IREC/CARS - Computer Assisted Robotic Surgery, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - SSS/IONS - Institute of NeuroScience, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'oto-rhino-laryngologie, UCL - (MGD) Service d'oncologie médicale |
| المصدر: | Head & neck, 41 (7 Head & neck, Vol. 41, no. 7, p. 2197-2207 (2019) Head and neck: journal for the sciences and specialties of the head and neck |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, Saliva, Oto-rhino-laryngologie, Side effect, Visual Analog Scale, Isometric exercise, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Swallowing, Tongue, medicine, Humans, Prospective Studies, radiotherapy, Aged, Aged, 80 and over, Hand Strength, Radiotherapy, business.industry, Head and neck cancer, tongue strength, Middle Aged, medicine.disease, Cancérologie, medicine.anatomical_structure, Otorhinolaryngology, quality of life, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Anesthesia, Quality of Life, head and neck cancer, Female, Human medicine, Bolus (digestion), business, Deglutition Disorders, swallowing, 030217 neurology & neurosurgery, Follow-Up Studies |
| الوصف: | Background Radiation-associated-dysphagia is a serious side effect of radiotherapy (RT) for head and neck cancer (HNC). Methods Seventy-six patients had a weekly prospective follow-up from baseline until one week post-RT. Combined mixed model analysis (n = 43) determined the evolution of self-perceived swallowing function, isometric tongue strength (MIP), tongue strength (TS) during swallowing (Pswal), and quality of life (QoL) in these patients during RT. Results Swallowing deteriorated from the third week on, resulting in an increase of tube dependency from 10% at baseline toward 31% post-RT. Both MIP and Pswal are reduced, with anterior MIP decreasing in 29% of patients and posterior MIP in 17%. Pswal decreases for saliva and a bolus swallow. All QoL subscales except "sleep" were affected during RT. Conclusions Self-perceived swallowing function, TS and QoL decrease during RT for HNC. Current findings highlight the need for early monitoring of these parameters. |
| وصف الملف: | 2 full-text file(s): application/pdf; application/pdf |
| تدمد: | 1097-0347 1043-3074 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4de54665d5ebcd898f4fc14e57cc918 https://pubmed.ncbi.nlm.nih.gov/30793811 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d4de54665d5ebcd898f4fc14e57cc918 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970347 10433074 |
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