Diet and Nutraceutical Supplementation in Dyslipidemic Patients: First Results of an Italian Single Center Real-World Retrospective Analysis
| العنوان: | Diet and Nutraceutical Supplementation in Dyslipidemic Patients: First Results of an Italian Single Center Real-World Retrospective Analysis |
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| المؤلفون: | Anna Laura Cremonini, Sabrina Piras, Andrea Pasta, Elena Formisano, Livia Pisciotta, Elio Maganza, Erika Parodi |
| المصدر: | Nutrients, Vol 12, Iss 2056, p 2056 (2020) Nutrients Volume 12 Issue 7 |
| بيانات النشر: | MDPI AG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, Mediterranean diet, 030204 cardiovascular system & hematology, Single Center, Diet, Mediterranean, Gastroenterology, 0302 clinical medicine, Risk Factors, Retrospective analysis, 030212 general & internal medicine, dyslipidemias, Nutrition and Dietetics, medicine.diagnostic_test, hypercholesterolemia, Anticholesteremic Agents, Middle Aged, Lipids, Cholesterol, Italy, Acute pancreatitis, Female, lipids (amino acids, peptides, and proteins), lcsh:Nutrition. Foods and food supply, Adult, medicine.medical_specialty, hypertriglyceridemia, EAS/ESC guidelines LDL-C targets, lcsh:TX341-641, Article, 03 medical and health sciences, Nutraceutical, Internal medicine, nutraceutical supplements, medicine, Humans, Triglycerides, Aged, Retrospective Studies, lipid lowering diet, business.industry, Hypertriglyceridemia, Cholesterol, LDL, medicine.disease, Atherosclerosis, Diet, Pancreatitis, Dietary Supplements, business, Lipid profile, Body mass index, Food Science |
| الوصف: | Background: Dyslipidemias are a heterogeneous group of metabolic disorders mainly characterized by an increased risk of atherosclerotic cardiovascular disease (ASCVD) or other conditions, such as acute pancreatitis in hypertriglyceridemia. The aim of this study was to evaluate the effect of diet treatment and nutraceutical (NUTs) supplementation on the plasma lipid profile in outpatient dyslipidemic subjects, considering the influence of several factors (i.e., gender, age, body mass index, alcohol consumption, and smoking habits). Methods: 487 dyslipidemic patients spanning from 2015 to 2019 were treated with a Mediterranean diet or NUTs in a real-word setting and were retrospectively analyzed. General characteristics and lipid profile at baseline and after the follow-up period were evaluated. Results: Diet alone reduced total cholesterol (&minus 19 mg/dL, &minus 7.7%), LDL cholesterol (&minus 18 mg/dL, &minus 10.1%), and triglycerides (&minus 20 mg/dL, &minus 16.7%). Triglycerides (TG) decreased more in men, while women were associated with higher reduction of LDL cholesterol (LDL-C). Different types of NUTs further ameliorate lipid profiles when associated with diet. Nevertheless, most patients at low ASCVD risk (222 out of 262, 81.6%) did not achieve the 2019 ESC/EAS guidelines recommended LDL-C goals (i.e., LDL-C < 116 mg/dL). Conclusion: Lipid-lowering diet improves lipid profile, and NUTs can boost its efficacy, but taken together they are mainly unsatisfactory with respect to the targets imposed by 2019 EAS/ESC guidelines. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c426ffc2d28d58b48d25181457ec03 https://www.mdpi.com/2072-6643/12/7/2056 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d4c426ffc2d28d58b48d25181457ec03 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726643 |
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