Costs of Point-of-Care Viral Load Testing for Adults and Children Living with HIV in Kenya
| العنوان: | Costs of Point-of-Care Viral Load Testing for Adults and Children Living with HIV in Kenya |
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| المؤلفون: | Leonard Kingwara, Lisa Abuogi, Monisha Sharma, Irene Mukui, Nashon Yongo, Evelyn Brown, Nancy Bowen, James Wagude, Michelle A Bulterys, Susan Njogo, Frederick Oluoch, Anjuli D. Wagner, Rena C Patel, Patrick Oyaro, Enericah Karauki |
| المصدر: | Diagnostics Volume 11 Issue 1 Diagnostics, Vol 11, Iss 140, p 140 (2021) |
| بيانات النشر: | MDPI, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, Cost estimate, costing, 030106 microbiology, Clinical Biochemistry, Human immunodeficiency virus (HIV), medicine.disease_cause, Article, 03 medical and health sciences, 0302 clinical medicine, Environmental health, medicine, Capital cost, 030212 general & internal medicine, Activity-based costing, health care economics and organizations, HIV management, Point of care, lcsh:R5-920, business.industry, Test (assessment), viral load test, point-of-care viral load testing, Staff time, HIV care, business, lcsh:Medicine (General), Viral load |
| الوصف: | Background: The number of people living with HIV (PLHIV) in need of treatment monitoring in low-and-middle-income countries is rapidly expanding, straining existing laboratory capacity. Point-of-care viral load (POC VL) testing can alleviate the burden on centralized laboratories and enable faster delivery of results, improving clinical outcomes. However, implementation costs are uncertain and will depend on clinic testing volume. We sought to estimate the costs of decentralized POC VL testing compared to centralized laboratory testing for adults and children receiving HIV care in Kenya. Methods: We conducted microcosting to estimate the per-patient costs of POC VL testing compared to known costs of centralized laboratory testing. We completed time-and-motion observations and stakeholder interviews to assess personnel structures, staff time, equipment costs, and laboratory processes associated with POC VL administration. Capital costs were estimated using a 5 year lifespan and a 3% annual discount rate. Results: We estimated that POC VL testing cost USD $24.25 per test, assuming a clinic is conducting 100 VL tests per month. Test cartridge and laboratory equipment costs accounted for most of the cost (62% and 28%, respectively). Costs varied by number of VL tests conducted at the clinic, ranging from $54.93 to $18.12 per test assuming 20 to 500 VL tests per month, respectively. A VL test processed at a centralized laboratory was estimated to cost USD $25.65. Conclusion: POC VL testing for HIV treatment monitoring can be feasibly implemented in clinics within Kenya and costs declined with higher testing volumes. Our cost estimates are useful to policymakers in planning resource allocation and can inform cost-effectiveness analyses evaluating POC VL testing. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2075-4418 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ae5002ac4e0db605159c2d181160a5 http://europepmc.org/articles/PMC7832863 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d2ae5002ac4e0db605159c2d181160a5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20754418 |
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