Restrictive Atrial Septum Defect Becomes a Risk Factor for Norwood Palliation of Hypoplastic Left Heart Syndrome Only When It Is Combined with Mitral or Aortic Atresia
| العنوان: | Restrictive Atrial Septum Defect Becomes a Risk Factor for Norwood Palliation of Hypoplastic Left Heart Syndrome Only When It Is Combined with Mitral or Aortic Atresia |
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| المؤلفون: | Nicodème Sinzobahamvya, Peter Zartner, Boulos Asfour, Viktor Hraska, S Sata, Claudia Arenz |
| المصدر: | The Thoracic and Cardiovascular Surgeon. 63:354-359 |
| بيانات النشر: | Georg Thieme Verlag KG, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Heart Defects, Congenital, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Kaplan-Meier Estimate, Norwood Procedures, Risk Assessment, Heart Septal Defects, Atrial, Statistics, Nonparametric, Hypoplastic left heart syndrome, Cohort Studies, Aortic Valve Atresia, Internal medicine, Mitral valve, Hypoplastic Left Heart Syndrome, Confidence Intervals, medicine, Humans, Abnormalities, Multiple, Retrospective Studies, Heart septal defect, business.industry, Infant, medicine.disease, Survival Analysis, Pulmonary hypertension, Norwood Operation, Stenosis, Treatment Outcome, medicine.anatomical_structure, Aortic Valve, Multivariate Analysis, Cardiology, Mitral Valve, Female, Surgery, Norwood procedure, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies |
| الوصف: | BACKGROUND Restrictive atrial septal defect (ASD) is described as risk factor for Norwood procedure because of elevated pulmonary resistance. We hypothesized that it invariably could not cause pulmonary hypertension, unless it was combined with mitral valve or aortic valve atresia. We investigated how restrictive ASD influenced survival of patients with hypoplastic left heart syndrome (HLHS) who underwent Norwood operation. PATIENTS AND METHODS A total of 118 HLHS patients who underwent surgery between January 2005 and December 2012 were grouped into three groups. Group 1 included 31 patients with restrictive ASD combined with mitral or aortic atresia; Group 2 composed of 12 patients with restrictive ASD and mitral and aortic stenosis; Group 3 (n = 75) had no ASD restriction. Survival was determined for each group. Multivariate analysis was conducted to test risk factors for mortality. RESULTS Mean follow-up was 26.3 ± 24.1 months. Survival was 78.7% ± 4.2% at 30-month interval and onward after Norwood procedure for the whole cohort; it was 43.8% ± 10.0%, 91.7% ± 8.0%, and 77.3% ± 5.0% for Group 1, 2, and 3, respectively. The difference was significant between Group 1 and Group 2 and 3: p |
| تدمد: | 1439-1902 0171-6425 |
| DOI: | 10.1055/s-0034-1374060 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27a477793bffc825042acfd2dc7ae5e https://doi.org/10.1055/s-0034-1374060 |
| رقم الانضمام: | edsair.doi.dedup.....d27a477793bffc825042acfd2dc7ae5e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14391902 01716425 |
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| DOI: | 10.1055/s-0034-1374060 |