Detecting short spatial scale local adaptation and epistatic selection in climate-related candidate genes in European beech (Fagus sylvatica) populations
| العنوان: | Detecting short spatial scale local adaptation and epistatic selection in climate-related candidate genes in European beech (Fagus sylvatica) populations |
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| المؤلفون: | Katalin Csilléry1, Hadrien Lalagüe1, 2, 3, Giovanni G. Vendramin3, Santiago C. González-Martínez4, Bruno Fady1, Sylvie Oddou-Muratorio1 |
| المساهمون: | Oddou-Muratorio, Sylvie, Ecologie des Forêts Méditerranéennes (URFM), Institut National de la Recherche Agronomique (INRA), Scuola Universitaria Superiore Sant'Anna [Pisa] (SSSUP), Consiglio Nazionale delle Ricerche (CNR), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria = National Institute for Agricultural and Food Research and Technology (INIA), ERA-Net BiodivERsA LINKTREE, ERA-Net BiodivERsA TipTree |
| المصدر: | Molecular Ecology 19 (23), 4696–4708 . (2014) Repositorio de Resultados de Investigación del INIA Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA Molecular Ecology Molecular Ecology, Wiley, 2014, 23 (19), pp.4696-4708. ⟨10.1111/mec.12902⟩ INIA: Repositorio de Resultados de Investigación del INIA Molecular ecology (2014). doi:10.1111/mec.12902 info:cnr-pdr/source/autori:Katalin Csilléry1,§, Hadrien Lalagüe1,2,3,§, Giovanni G. Vendramin3, Santiago C. González-Martínez4, Bruno Fady1 and Sylvie Oddou-Muratorio1*/titolo:Detecting short spatial scale local adaptation and epistatic selection in climate-related candidate genes in European beech (Fagus sylvatica) populations/doi:10.1111%2Fmec.12902/rivista:Molecular ecology (Print)/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | 0106 biological sciences, Nonsynonymous substitution, Candidate gene, Linkage disequilibrium, haplotype, Acclimatization, Biodiversité et Ecologie, approche gène candidat, déséquilibre de linkage, 01 natural sciences, différenciation génétique, Fagus, échelle locale, mont ventoux, sud de la france, Genetics, 0303 health sciences, variance components of linkage disequilibrium, biology, analyse multilocale, gene network, France, abiotic stress, budburst phenology, F-ST outlier, Ohta's test, DNA, Plant, signature de sélection, Climate Change, fagus sylvatica, 010603 evolutionary biology, Polymorphism, Single Nucleotide, FST outlier, inférence statistique, Biodiversity and Ecology, adaptation au climat, 03 medical and health sciences, Selection, Genetic, Beech, Ecology, Evolution, Behavior and Systematics, Selection (genetic algorithm), Alleles, 030304 developmental biology, Local adaptation, stress abiotique, Models, Genetic, variance epistatique, Haplotype, Bayes Theorem, Epistasis, Genetic, Sequence Analysis, DNA, 15. Life on land, biology.organism_classification, Genetics, Population, Haplotypes, 13. Climate action, Epistasis, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Microsatellite Repeats |
| الوصف: | Detecting signatures of selection in tree populations threatened by climate change is currently a major research priority. Here, we investigated the signature of local adaptation over a short spatial scale using 96 European beech (Fagus sylvatica L.) individuals originating from two pairs of populations on the northern and southern slopes of Mont Ventoux (south-eastern France). We performed both single and multi-locus analysis of selection based on 53 climaterelated candidate genes containing 546 SNPs. FST outlier methods at the SNP level revealed a Accepted Article This article is protected by copyright. All rights reserved. weak signal of selection, with three marginally significant outliers in the northern populations. At the gene-level, considering haplotypes as alleles, two additional marginally significant outliers were detected, one on each slope. To account for the uncertainty of haplotype inference, we averaged the Bayes Factors over many possible phase reconstructions. Epistatic selection offers a realistic multi-locus model of selection in natural populations. Here, we used a test suggested by Ohta based on the decomposition of the variance of linkage disequilibrium. Over all populations, 0.23% of the SNP pairs (haplotypes) showed evidence of epistatic selection, with nearly 80% of them being within genes. One of the between gene epistatic selection signals arose between an FST outlier and a nonsynonymous mutation in a drought response gene. Additionally, we identified haplotypes containing selectively advantageous allele combinations which were unique to high or lowelevations and northern or southern populations. Several haplotypes contained nonsynonymous mutations situated in genes with known functional importance for adaptation to climatic factors. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0962-1083 1365-294X |
| DOI: | 10.1111/mec.12902⟩ |
| DOI: | 10.1111/mec.12902 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d180db048b5656b2dd67315129740711 http://prodinra.inra.fr/record/269593 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d180db048b5656b2dd67315129740711 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 09621083 1365294X |
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| DOI: | 10.1111/mec.12902⟩ |