Hyperbolic rules of the cooperative organization of eukaryotic and prokaryotic genomes
| العنوان: | Hyperbolic rules of the cooperative organization of eukaryotic and prokaryotic genomes |
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| المؤلفون: | Petoukhov, Sergey V. |
| المصدر: | Bio Systems Biosystems |
| بيانات النشر: | Elsevier BV, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Statistics and Probability, Genomics, Hyperbolic rules, Computational biology, Genome, Article, General Biochemistry, Genetics and Molecular Biology, DNA sequencing, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Modelling and Simulation, Genomes, Algebraic number, Gene, 030304 developmental biology, 0303 health sciences, Harmonic progression, SARS-CoV-2, Applied Mathematics, Proteins, Eukaryota, General Medicine, Tensor product, Quantum informatics, Oligomer sums method, Eukaryotic Cells, Genes, Prokaryotic Cells, chemistry, Modeling and Simulation, Viruses, Human genome, 030217 neurology & neurosurgery, DNA |
| الوصف: | The author's method of oligomer sums for analysis of oligomer compositions of eukaryotic and prokaryotic genomes is described. The use of this method revealed the existence of general rules for the cooperative oligomeric organization of a wide list of genomes. These rules are called hyperbolic because they are associated with hyperbolic sequences including the harmonic progression 1, 1/2, 1/3, .., 1/n. These rules are demonstrated by examples of quantitative analysis of many genomes from the human genome to the genomes of archaea and bacteria. The hyperbolic (harmonic) rules, speaking about the existence of algebraic invariants in full genomic sequences, are considered as candidates for the role of universal rules for the cooperative organization of genomes. The results concerns additionally the problem of the origin of life. The described phenomenological results were obtained as consequences of the previously published author's quantum-information model of long DNA sequences. The oligomer sums method was also applied to the analysis of long genes and viruses including the COVID-19 virus; this revealed, in characteristics of many of them, the phenomenon of such rhythmically repeating deviations from model hyperbolic sequences, which are associated with DNA triplets. In addition, an application of the oligomer sums method is shown to the analysis of amino acid sequences in long proteins like the protein Titin. The topics of the algebraic harmony in living bodies and of the quantum-information approach in biology are discussed. |
| تدمد: | 0303-2647 |
| DOI: | 10.1016/j.biosystems.2020.104273 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ccc5529fa0e8b3dc6143128dcc9e5b https://doi.org/10.1016/j.biosystems.2020.104273 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d0ccc5529fa0e8b3dc6143128dcc9e5b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 03032647 |
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| DOI: | 10.1016/j.biosystems.2020.104273 |