Histone Demethylases as Counterbalance to H3K27me3 Silencing in Plants
| العنوان: | Histone Demethylases as Counterbalance to H3K27me3 Silencing in Plants |
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| المؤلفون: | Pedro Crevillén |
| المصدر: | iScience, Vol 23, Iss 11, Pp 101715-(2020) iScience |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, Multidisciplinary, biology, fungi, Plant Biology, Plant Development, Review, 02 engineering and technology, Biological Sciences, 021001 nanoscience & nanotechnology, Cell biology, 03 medical and health sciences, Histone lysine demethylation, Histone H3, 030104 developmental biology, Histone, Gene expression, biology.protein, Gene silencing, lcsh:Q, Histone Demethylases, Epigenetics, 0210 nano-technology, Histone demethylase activity, lcsh:Science |
| الوصف: | Summary The universal importance of epigenetic regulation has become explicit over the last decade. There is now a detailed understanding of the molecular signatures and chromatin-modifying enzymes determining epigenetic regulation. For example, the trimethylation of lysine 27 at histone H3 by Polycomb complexes is a hallmark of silenced gene expression conserved across animal and plant kingdoms. The repressive activity of Polycomb complexes is balanced by the histone demethylase activity of Jumonji C-domain proteins. There has been a lot of research on Polycomb functions and H3K27 methylation; however, until recently, little was known about the role of histone H3K27 demethylases. Here, we review the role of Jumonji C-domain proteins from the plant development perspective. We will recall the history of histone lysine demethylation and explore the recent advances on the H3K27 demethylases in plant biology. Conserved and novel genomic functions of these epigenetic regulators will be discussed. Graphical Abstract Highlights • Jumonji C-domain proteins demethylate the repressive epigenetic mark H3K27me3 • Plant H3K27me3 demethylases include ELF6, REF6, JMJ13, JMJ30, and JMJ32 • Plant H3K27me3 demethylases regulate a wide range of developmental processes Biological Sciences; Plant Biology; Plant Development |
| اللغة: | English |
| تدمد: | 2589-0042 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd774425a6ea5aaf704dbf41c6b1f081 http://www.sciencedirect.com/science/article/pii/S2589004220309123 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....cd774425a6ea5aaf704dbf41c6b1f081 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25890042 |
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