Multi-port versus single-port cholecystectomy: results of a multi-centre, randomised controlled trial (MUSIC trial)
| العنوان: | Multi-port versus single-port cholecystectomy: results of a multi-centre, randomised controlled trial (MUSIC trial) |
|---|---|
| المؤلفون: | I. Kazakov, Riccardo Rosati, Antonio M. Lacy, Rudolf Schrittwieser, Amir Szold, Kirill Shishin, Maurizio Degiuli, Igor Khatkov, Mario Sorrentino, Giuseppe Navarra, Lazzara S, Nicola Di Lorenzo, Elisa Cassinotti, Achille L. Gaspari, Guenther Sitzman, Yoav Mintz, Alberto Arezzo, Asaf Kedar, Dario Andreone, Marco Brizzolari, Alberto Bullano, Elena De Stefani, Roberto Passera, Mario Morino, Alessio Corradi, Uberto Fumagalli Romario, Thomas Carus, Selman Uranues, Luigi Boni |
| المساهمون: | Arezzo, Alberto, Passera, Roberto, Bullano, Alberto, Mintz, Yoav, Kedar, Asaf, Boni, Luigi, Cassinotti, Elisa, Rosati, Riccardo, Fumagalli Romario, Uberto, Sorrentino, Mario, Brizzolari, Marco, Di Lorenzo, Nicola, Gaspari, Achille Lucio, Andreone, Dario, De Stefani, Elena, Navarra, Giuseppe, Lazzara, Salvatore, Degiuli, Maurizio, Shishin, Kirill, Khatkov, Igor, Kazakov, Ivan, Schrittwieser, Rudolf, Carus, Thoma, Corradi, Alessio, Sitzman, Guenther, Lacy, Antonio, Uranues, Selman, Szold, Amir, Morino, Mario |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Laparoscopic surgery, Adult, Male, medicine.medical_specialty, Adolescent, Incisional hernia, medicine.medical_treatment, Operative Time, Gallbladder Diseases, 030230 surgery, law.invention, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Patient satisfaction, Laparoscopic, Postoperative Complications, Randomized controlled trial, law, medicine, Humans, Cholecystectomy, Prospective Studies, Laparoscopy, Aged, Intention-to-treat analysis, medicine.diagnostic_test, business.industry, General surgery, Middle Aged, medicine.disease, Surgery, Settore MED/18, Treatment Outcome, Cholecystectomy, Laparoscopic, Cholecystectomy, Randomized controlled trial, Single port surgery, Adolescent, Adult, Aged, Cholecystectomy, Laparoscopic, Female, Follow-Up Studies, Gallbladder Diseases, Humans, Male, Middle Aged, Operative Time, Patient Satisfaction, Postoperative Complications, Prospective Studies, Treatment Outcome, Young Adult, Surgery, Single port surgery, Patient Satisfaction, 030211 gastroenterology & hepatology, Female, business, Abdominal surgery, Follow-Up Studies |
| الوصف: | Background: Single-port laparoscopic surgery as an alternative to conventional laparoscopic cholecystectomy for benign disease has not yet been accepted as a standard procedure. The aim of the multi-port versus single-port cholecystectomy trial was to compare morbidity rates after single-access (SPC) and standard laparoscopy (MPC). Methods: This non-inferiority phase 3 trial was conducted at 20 hospital surgical departments in six countries. At each centre, patients were randomly assigned to undergo either SPC or MPC. The primary outcome was overall morbidity within 60 days after surgery. Analysis was by intention to treat. The study was registered with ClinicalTrials.gov (NCT01104727). Results: The study was conducted between April 2011 and May 2015. A total of 600 patients were randomly assigned to receive either SPC (n = 297) or MPC (n = 303) and were eligible for data analysis. Postsurgical complications within 60 days were recorded in 13 patients (4.7 %) in the SPC group and in 16 (6.1 %) in the MPC group (P = 0.468); however, single-access procedures took longer [70 min (range 25â265) vs. 55 min (range 22â185); P |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd74252b7c13390f16b1309f25648a9f https://hdl.handle.net/2108/314276 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....cd74252b7c13390f16b1309f25648a9f |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |