Irreversible Electroporation Balloon Therapy for Palliative Treatment of Obstructive Urethral Transitional Cell Carcinoma in Dogs
| العنوان: | Irreversible Electroporation Balloon Therapy for Palliative Treatment of Obstructive Urethral Transitional Cell Carcinoma in Dogs |
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| المؤلفون: | Emmanuelle, Marie Butty, Bruce, Forsyth, Mary Anna, Labato |
| المصدر: | Journal of the American Animal Hospital Association. 58:231-239 |
| بيانات النشر: | American Animal Hospital Association, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Carcinoma, Transitional Cell, Dogs, Electroporation, Urethral Obstruction, Palliative Care, Animals, Dog Diseases, Small Animals |
| الوصف: | Progression of transitional cell carcinoma (TCC) in dogs often leads to urinary obstruction. This observational pilot study aimed to evaluate the safety and efficacy of irreversible electroporation (IRE) balloon therapy for the palliative treatment of TCC with partial urethral obstruction. Three client-owned dogs diagnosed with TCC causing partial urethral obstruction were enrolled. After ultrasonographic and cystoscopic examination, IRE pulse protocols were delivered through a balloon catheter device inflated within the urethral lumen. After the procedure, the patients were kept overnight for monitoring and a recheck was planned 28 days later. No complication was observed during the procedure and postprocedural monitoring. After 28 days, one dog had a complete normalization of the urine stream, one dog had stable stranguria, and one dog was presented with a urethral obstruction secondary to progression of the TCC. On recheck ultrasound, one dog had a 38% diminution of the urethral mass diameter whereas the other two dogs had a mass stable in size. IRE balloon therapy seems to be a feasible and apparently safe minimally invasive novel therapy for the palliative treatment of TCC causing urethral obstruction. Further studies are needed to better characterize the safety, efficacy, and outcome of this therapy. |
| تدمد: | 1547-3317 0587-2871 |
| DOI: | 10.5326/jaaha-ms-7160 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbbaec7117d7a60681e346621729c7b https://doi.org/10.5326/jaaha-ms-7160 |
| رقم الانضمام: | edsair.doi.dedup.....cbbbaec7117d7a60681e346621729c7b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15473317 05872871 |
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| DOI: | 10.5326/jaaha-ms-7160 |