General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process
| العنوان: | General Design Strategy to Precisely Control the Emission of Fluorophores via a Twisted Intramolecular Charge Transfer (TICT) Process |
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| المؤلفون: | Kenjiro Hanaoka, Shimpei Iwaki, Kiyoshi Yagi, Takuya Myochin, Takayuki Ikeno, Hisashi Ohno, Eita Sasaki, Toru Komatsu, Tasuku Ueno, Motokazu Uchigashima, Takayasu Mikuni, Kazuki Tainaka, Shinya Tahara, Satoshi Takeuchi, Tahei Tahara, Masanobu Uchiyama, Tetsuo Nagano, Yasuteru Urano |
| المصدر: | Journal of the American Chemical Society. 144:19778-19790 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Colloid and Surface Chemistry, Ionophores, Rhodamines, Fluorescence Resonance Energy Transfer, General Chemistry, Biochemistry, Catalysis, Fluorescent Dyes |
| الوصف: | Fluorogenic probes for bioimaging have become essential tools for life science and medicine, and the key to their development is a precise understanding of the mechanisms available for fluorescence off/on control, such as photoinduced electron transfer (PeT) and Förster resonance energy transfer (FRET). Here we establish a new molecular design strategy to rationally develop activatable fluorescent probes, which exhibit a fluorescence off/on change in response to target biomolecules, by controlling the twisted intramolecular charge transfer (TICT) process. This approach was developed on the basis of a thorough investigation of the fluorescence quenching mechanism of |
| تدمد: | 1520-5126 0002-7863 |
| DOI: | 10.1021/jacs.2c06397 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0faea991add1d0b00aa35c9beea5ef https://doi.org/10.1021/jacs.2c06397 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....cb0faea991add1d0b00aa35c9beea5ef |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15205126 00027863 |
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| DOI: | 10.1021/jacs.2c06397 |