Structure-Based Prototyping of Allosteric Inhibitors of Human Uridine/Cytidine Kinase 2 (UCK2)
| العنوان: | Structure-Based Prototyping of Allosteric Inhibitors of Human Uridine/Cytidine Kinase 2 (UCK2) |
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| المؤلفون: | Siavash Mashayekh, Lee M. Stunkard, Maryline Kienle, Irimpan I. Mathews, Chaitan Khosla |
| المصدر: | Biochemistry. 61:2261-2266 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Humans, Pyrimidine Nucleotides, Uridine Kinase, Uridine, Biochemistry |
| الوصف: | Pyrimidine nucleotide biosynthesis in humans is a promising chemotherapeutic target for infectious diseases caused by RNA viruses. Because mammalian cells derive pyrimidine ribonucleotides through a combination of |
| تدمد: | 1520-4995 0006-2960 |
| DOI: | 10.1021/acs.biochem.2c00451 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c927f48e3caadc07ccd33fca9e30f76e https://doi.org/10.1021/acs.biochem.2c00451 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....c927f48e3caadc07ccd33fca9e30f76e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15204995 00062960 |
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| DOI: | 10.1021/acs.biochem.2c00451 |