Severe Hypoglycaemia Leading to Hospital Admission in Type 2 Diabetic Patients Aged 80 Years or Older

التفاصيل البيبلوغرافية
العنوان: Severe Hypoglycaemia Leading to Hospital Admission in Type 2 Diabetic Patients Aged 80 Years or Older
المؤلفون: M. Pisciotta, D. Greco, F. Gambina, F. Maggio
المصدر: Experimental and Clinical Endocrinology & Diabetes. 118:215-219
بيانات النشر: Georg Thieme Verlag KG, 2010.
سنة النشر: 2010
مصطلحات موضوعية: Male, Pediatrics, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, Hypoglycemia, Diabetes Therapy, Patient Admission, Endocrinology, Risk Factors, Diabetes management, Diabetes mellitus, Glyburide, Internal Medicine, Humans, Hypoglycemic Agents, Medicine, Risk factor, Aged, 80 and over, Blood glucose monitoring, medicine.diagnostic_test, business.industry, Blood Glucose Self-Monitoring, Incidence, General Medicine, medicine.disease, Comorbidity, Surgery, Hospitalization, Glucose, Diabetes Mellitus, Type 2, Female, business
الوصف: Aim: Evidence is mounting that hypoglycaemia among elderly diabetic patients is a very real and costly concern. Objective of this study was to determine the incidence and risk factors for developing severe hypoglycaemia leading to hospital admission, among type 2 diabetic subjects aged 80 years or older. Methods: Hypoglycaemia was defined as a symptomatic event requiring treatment with i.v. glucose and confirmed by a blood glucose determination < 50 mg/dl. Results: During a eight-year period severe hypoglycaemia was identified in 99 subjects. These patients were found to have a reduced cognitive ability, a heavy burden of comorbid disease and a HbA1c values of 5.9 %. Of the hypoglycaemic episodes, 76 occurred in patients taking glibenclamide. Diabetes therapy was prescribed by general practitioners in 85 of them. Only 26 patients performed regular home blood glucose self-monitoring. Conclusion: Severe hypoglycaemia is a serious and not uncommon metabolic emergency among patients with type 2 diabetes aged 80 years or older; it is more frequent in patients with considerable comorbidity undergoing aggressive diabetes management and in users of a long-acting sulphonylurea. In elderly subject, each patient's risk for hypoglycaemia should be considered and therapy should be individualized accordingly; in our opinion, a great number of episodes may be avoided by teaching the principles of blood glucose monitoring and involving general practitioners in outpatients management of diabetes mellitus.
تدمد: 1439-3646
0947-7349
DOI: 10.1055/s-0029-1241823
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83c0c1a6e5a150df7cc1bfa8284069b
https://doi.org/10.1055/s-0029-1241823
رقم الانضمام: edsair.doi.dedup.....c83c0c1a6e5a150df7cc1bfa8284069b
قاعدة البيانات: OpenAIRE
الوصف
تدمد:14393646
09477349
DOI:10.1055/s-0029-1241823