Various Strategies in Post-Polymerization Functionalization of Organic Polymer-Based Monoliths Used in Liquid Phase Separation Techniques
| العنوان: | Various Strategies in Post-Polymerization Functionalization of Organic Polymer-Based Monoliths Used in Liquid Phase Separation Techniques |
|---|---|
| المؤلفون: | Ziad El Rassi, Sarah Alharthi |
| المصدر: | Molecules Molecules, Vol 25, Iss 6, p 1323 (2020) |
| بيانات النشر: | MDPI, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Fabrication, Materials science, Polymers, Liquid-Liquid Extraction, Pharmaceutical Science, Liquid phase, Nanotechnology, 02 engineering and technology, Review, capillary LC, 01 natural sciences, Analytical Chemistry, Polymerization, lcsh:QD241-441, lcsh:Organic chemistry, Polymethacrylic Acids, Drug Discovery, Physical and Theoretical Chemistry, Monolith, Organic Chemicals, Organic polymer, Capillary electrochromatography, geography, geography.geographical_feature_category, 010401 analytical chemistry, Organic Chemistry, capillary electrochromatography, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Organic reaction, Chemistry (miscellaneous), organic polymer monoliths, Molecular Medicine, Surface modification, Click Chemistry, HPLC, 0210 nano-technology, Post polymerization, post-polymerization functionalization |
| الوصف: | This review article is aimed at summarizing the various strategies that have been developed so far for post-polymerization functionalization (PPF) of organic polymer-based monoliths used in liquid phase separation techniques, namely HPLC at all scales and capillary electrochromatography (CEC). The reader will find the organic reactions performed on monolithic columns for grafting the chromatographic ligands needed for solving the separation problems on hand. This process involves therefore the fabrication of template monoliths that carry reactive functional groups to which chromatographic ligands can be covalently attached in a post-polymerization kind of approach. That is, the template monolith that has been optimized in terms of pore structure and other morphology can be readily modified and tailor made on column to fit a particular separation. The review article will not only cover the various strategies developed so far but also describe their separation applications. To the best of our knowledge, this review article will be the first of its kind. |
| اللغة: | English |
| تدمد: | 1420-3049 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82f924e9b433ef98628f55c2b446b85 http://europepmc.org/articles/PMC7144949 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c82f924e9b433ef98628f55c2b446b85 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14203049 |
|---|