Renoprotective effects of topiroxostat for Hyperuricaemic patients with overt diabetic nephropathy study (ETUDE study): A prospective, randomized, multicentre clinical trial
| العنوان: | Renoprotective effects of topiroxostat for Hyperuricaemic patients with overt diabetic nephropathy study (ETUDE study): A prospective, randomized, multicentre clinical trial |
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| المؤلفون: | Hideaki Shimizu, Norimi Ohashi, Masahiko Ando, Tomohiko Naruse, Takanobu Nagata, Toshihiro Mizukoshi, Yosuke Saka, Hiroshi Sobajima, Sawako Kato, Shoichi Maruyama |
| المصدر: | Nephrology. 23(11):1023-1030 |
| بيانات النشر: | Wiley, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Randomization, Pyridines, 030232 urology & nephrology, Urology, Renal function, Blood Pressure, Hyperuricemia, 030204 cardiovascular system & hematology, Fatty Acid-Binding Proteins, Kidney, albuminuria, law.invention, Diabetic nephropathy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, Nitriles, medicine, Clinical endpoint, Humans, Diabetic Nephropathies, Prospective Studies, topiroxostat, Aged, Aged, 80 and over, Glycated Hemoglobin, Creatinine, Proteinuria, business.industry, diabetic nephropathy, General Medicine, Middle Aged, medicine.disease, Surgery, xanthine oxidoreductase inhibitor, chemistry, Nephrology, Albuminuria, Female, medicine.symptom, business, randomized study, Glomerular Filtration Rate |
| الوصف: | Aim: We aimed to evaluate the anti‐albuminuric effects of topiroxostat in Japanese hyperuricaemic patients with diabetic nephropathy. Methods: In this 24‐week, multicentre, open‐label, randomized (1 : 1) trial, we assigned hyperuricaemic patients with diabetic nephropathy (estimated glomerular filtration rate ≥ 20 mL/min per 1.73m2) and overt proteinuria (0.3 ≤ urine protein to creatinine ratio (UPCR) ファイル公開：2019-11-01 |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1320-5358 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cd6806969e3e4166ba4fffc08f1b1b https://nagoya.repo.nii.ac.jp/records/27083 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c7cd6806969e3e4166ba4fffc08f1b1b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13205358 |
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