Dose-Dependent Associations of Dietary Glycemic Index, Glycemic Load, and Fiber With 3-Year Weight Loss Maintenance and Glycemic Status in a High-Risk Population: A Secondary Analysis of the Diabetes Prevention Study PREVIEW
| العنوان: | Dose-Dependent Associations of Dietary Glycemic Index, Glycemic Load, and Fiber With 3-Year Weight Loss Maintenance and Glycemic Status in a High-Risk Population: A Secondary Analysis of the Diabetes Prevention Study PREVIEW |
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| المؤلفون: | Mikael Fogelholm, Tanja C. Adam, Pia Siig Vestentoft, Mathijs Drummen, Gareth Stratton, Anne Raben, Ruixin Zhu, Roslyn Muirhead, Maija Huttunen-Lenz, Thomas Meinert Larsen, Christian Ritz, Sally D. Poppitt, Svetoslav Handjiev, Ian A. Macdonald, Moira A. Taylor, J. Alfredo Martínez, Nils Swindell, Shannon Brodie, Elli Jalo, Marta P. Silvestre, Teodora Handjieva-Darlenska, Margriet S. Westerterp-Plantenga, Santiago Navas-Carretero, Jouko Sundvall, Jennie Brand-Miller, Liisa Valsta |
| المساهمون: | Nutrition and Movement Sciences, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, Humane Biologie, Department of Food and Nutrition |
| المصدر: | Diabetes Care, 44(7), 1672-1681. American Diabetes Association Diabetes Care |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Cardiovascular and Metabolic Risk, medicine.medical_specialty, BODY-COMPOSITION, OVERWEIGHT SUBJECTS, IMPACT, Endocrinology, Diabetes and Metabolism, Population, 030209 endocrinology & metabolism, Type 2 diabetes, Overweight, 03 medical and health sciences, 0302 clinical medicine, PROGRAMS, Weight loss, Surveys and Questionnaires, Internal medicine, Weight Loss, Glycemic load, Internal Medicine, medicine, Humans, 030212 general & internal medicine, Prediabetes, education, LOW-PROTEIN CONTENT, Aged, Glycemic, Advanced and Specialized Nursing, education.field_of_study, business.industry, Glycemic Load, Middle Aged, medicine.disease, Diet, 3. Good health, Glycemic index, Diabetes Mellitus, Type 2, Glycemic Index, 3121 General medicine, internal medicine and other clinical medicine, 3143 Nutrition, medicine.symptom, business |
| الوصف: | OBJECTIVE To examine longitudinal and dose-dependent associations of dietary glycemic index (GI), glycemic load (GL), and fiber with body weight and glycemic status during 3-year weight loss maintenance (WLM) in adults at high risk of type 2 diabetes. RESEARCH DESIGN AND METHODS In this secondary analysis we used pooled data from the PREVention of diabetes through lifestyle Intervention and population studies in Europe and around the World (PREVIEW) randomized controlled trial, which was designed to test the effects of four diet and physical activity interventions. A total of 1,279 participants with overweight or obesity (age 25–70 years and BMI ≥25 kg ⋅ m−2) and prediabetes at baseline were included. We used multiadjusted linear mixed models with repeated measurements to assess longitudinal and dose-dependent associations by merging the participants into one group and dividing them into GI, GL, and fiber tertiles, respectively. RESULTS In the available-case analysis, each 10-unit increment in GI was associated with a greater regain of weight (0.46 kg ⋅ year−1; 95% CI 0.23, 0.68; P < 0.001) and increase in HbA1c. Each 20-unit increment in GL was associated with a greater regain of weight (0.49 kg ⋅ year−1; 0.24, 0.75; P < 0.001) and increase in HbA1c. The associations of GI and GL with HbA1c were independent of weight change. Compared with those in the lowest tertiles, participants in the highest GI and GL tertiles had significantly greater weight regain and increases in HbA1c. Fiber was inversely associated with increases in waist circumference, but the associations with weight regain and glycemic status did not remain robust in different analyses. CONCLUSIONS Dietary GI and GL were positively associated with weight regain and deteriorating glycemic status. Stronger evidence on the role of fiber is needed. |
| اللغة: | English |
| تدمد: | 0149-5992 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6681a431f464ed5d29744cc94b7d25d https://cris.maastrichtuniversity.nl/en/publications/b439c4b1-2162-4302-a50d-9c73236233ce |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c6681a431f464ed5d29744cc94b7d25d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 01495992 |
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