Dual Role of Oxoaldehydes: Divergent Synthesis of 3-Aryl- and 3-Aroylcoumarins
| العنوان: | Dual Role of Oxoaldehydes: Divergent Synthesis of 3-Aryl- and 3-Aroylcoumarins |
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| المؤلفون: | Ali Moazzam, Meysam Khodadadi, Farnaz Jafarpour, Mehdi Ghandi |
| المصدر: | The Journal of Organic Chemistry. 87:3630-3637 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Coumarins, Metals, Organic Chemistry, Indicators and Reagents |
| الوصف: | A facile and efficient synthetic approach to various valuable 3-aryl- and 3-aroylcoumarins by the direct arylation and aroylation of coumarins with glyoxals in a metal-free manner is presented. The aryl glyoxal is for the first time recognized to serve as an aryl surrogate in addition to its role as an aroyl transfer reagent via a simple switch in reaction conditions. The approach accommodates a broad substrate scope and high yields of the two types of cross-coupling reactions starting from identical starting materials. |
| تدمد: | 1520-6904 0022-3263 |
| DOI: | 10.1021/acs.joc.1c02159 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20db319c1f087c980c22e57a837b0af https://doi.org/10.1021/acs.joc.1c02159 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....c20db319c1f087c980c22e57a837b0af |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15206904 00223263 |
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| DOI: | 10.1021/acs.joc.1c02159 |