Genotyping of Human Papillomavirus in Cervical Squamous Intraepithelial Lesions in Mexican Women
| العنوان: | Genotyping of Human Papillomavirus in Cervical Squamous Intraepithelial Lesions in Mexican Women |
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| المؤلفون: | Sergio Martínez-Pérez, Hugo Mendieta-Zerón, Michelle Pérez-Rogel, Ma . Victoria Domínguez-García, María del Carmen Colín-Ferreyra, Migdania Martínez-Madrigal, María Del Socorro Camarillo-Romero, María del Socorro Romero-Figueroa |
| المصدر: | Japanese journal of infectious diseases. 73(2) |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Microbiology (medical), Adult, medicine.medical_specialty, Genotype, Genotyping Techniques, Squamous Intraepithelial Lesions, 030106 microbiology, Population, Uterine Cervical Neoplasms, Cervix Uteri, Cervical intraepithelial neoplasia, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, medicine, Humans, 030212 general & internal medicine, Risk factor, education, Genotyping, Mexico, Papillomaviridae, Colposcopy, Cervical cancer, education.field_of_study, medicine.diagnostic_test, business.industry, Papillomavirus Infections, HPV infection, virus diseases, General Medicine, medicine.disease, Uterine Cervical Dysplasia, female genital diseases and pregnancy complications, Infectious Diseases, Cross-Sectional Studies, DNA, Viral, Female, business |
| الوصف: | Approximately 40 genotypes of the human papillomavirus (HPV) have been identified in cervical mucosa. In particular, HPV-16 and HPV-18 have been associated with cervical neoplasia. Squamous intraepithelial lesions (SILs) are precursors of cervical cancer. This study aimed to identify the HPV by genotype in SILs using a linear array genotyping test in a population in Mexico. We performed a cross-sectional study of 129 female patients with or without SILs, as determined by colposcopy, who completed a risk factor questionnaire. Cervical swab samples were obtained and genotyped using a Linear Array HPV Genotyping assay. Forty-nine (37.98%) samples were positive for HPV, and 24 genotypes were identified among these samples. The most common genotype was HPV-16. Twelve genotypes were found in both high- and low-grade SILs (HPV-6, 16, 31, 39, 51, 52, 53, 58, 59, 61, 67, and 84), of which seven were high-risk SILs (HPV-16, 31, 39, 51, 52, 58, and 59). Among the populations studied, the most frequent genotype was HPV-16, multiple infections were found, and four patients without injury tested positive for HPV. |
| تدمد: | 1884-2836 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10b976872cfc3d184be0f5b51d0f38d https://pubmed.ncbi.nlm.nih.gov/31787740 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c10b976872cfc3d184be0f5b51d0f38d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18842836 |
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