Genetic Counseling for Early‐onset Familial Alzheimer Disease in Large Aboriginal Kindred from a Remote Community in British Columbia: Unique Challenges and Possible Solutions
| العنوان: | Genetic Counseling for Early‐onset Familial Alzheimer Disease in Large Aboriginal Kindred from a Remote Community in British Columbia: Unique Challenges and Possible Solutions |
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| المؤلفون: | A. Dessa Sadovnick, Colleen Guimond, Rachel Butler, Judy Illes, Sofia Lombera, Elana Brief, B. Lynn Beattie, Emily Dwosh |
| المصدر: | Journal of Genetic Counseling. 20:136-142 |
| بيانات النشر: | Wiley, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Gerontology, Cultural Characteristics, British Columbia, business.industry, Genetic counseling, Genetic Counseling, medicine.disease, Aboriginal community, Presenilin, Patient Education as Topic, Alzheimer Disease, Mutation (genetic algorithm), medicine, Humans, Continuity of care, Alzheimer's disease, business, Genetics (clinical), Early onset |
| الوصف: | A novel, pathogenic presenilin 1 (PS1) mutation has recently been identified in a large Aboriginal kindred living in dispersed communities throughout British Columbia, Canada. Disseminating genetic information and ensuring that appropriate genetic counseling services are provided to all concerned relatives have posed several unique challenges. These challenges include knowledge exchange and continuity of care in a geographically remote and culturally distinct community. To our knowledge, this is the first time a specific genetic counseling approach has been needed for early-onset familial Alzheimer disease (EOFAD) in a North American Aboriginal community. |
| تدمد: | 1573-3599 1059-7700 |
| DOI: | 10.1007/s10897-010-9334-9 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07af087275dade27783b05d15a1d06a https://doi.org/10.1007/s10897-010-9334-9 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....c07af087275dade27783b05d15a1d06a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15733599 10597700 |
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| DOI: | 10.1007/s10897-010-9334-9 |