Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern
| العنوان: | Association of the intronic rs2072621 polymorphism of the X-linked GPR50 gene with affective disorder with seasonal pattern |
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| المؤلفون: | M.-F. Poirier, M. Delavest, C. Even, N. Benjemaa, Ralf Jockers, Marie-Odile Krebs |
| المصدر: | European Psychiatry. 27:369-371 |
| بيانات النشر: | Cambridge University Press (CUP), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Male, Subfamily, Genotype, Nerve Tissue Proteins, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, Melatonin receptor, Genetic determinism, Receptors, G-Protein-Coupled, Melatonin, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Genes, X-Linked, medicine, Humans, Genetic Predisposition to Disease, Gene, Genetic Association Studies, Genetics, 030505 public health, Seasonal Affective Disorder, 030229 sport sciences, medicine.disease, Introns, Psychiatry and Mental health, Mood disorders, GPR50, Case-Control Studies, Female, 0305 other medical science, medicine.drug |
| الوصف: | This case-control study found an association between Seasonal Affective Disorder (SAD) and a single nucleotide polymorphism (intronic rs2072621) of the gene encoding GPR50 (an orphan member of the G protein-coupled melatonin receptor subfamily) in females. This may represent a gender-specific risk factor and a molecular link between melatonin and SAD. |
| تدمد: | 1778-3585 0924-9338 |
| DOI: | 10.1016/j.eurpsy.2011.02.011 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfea31c44725fb285460fdc52d9f1fd8 https://doi.org/10.1016/j.eurpsy.2011.02.011 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bfea31c44725fb285460fdc52d9f1fd8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17783585 09249338 |
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| DOI: | 10.1016/j.eurpsy.2011.02.011 |