Histopathologic assessment of the entire endometrium in asymptomatic women
| العنوان: | Histopathologic assessment of the entire endometrium in asymptomatic women |
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| المؤلفون: | Johanna M.A. Pijnenborg, Maaike A.P.C. van Ham, Angela A.G. van Tilborg, Johan Bulten, Anneke A. M. van der Wurff, Leon F.A.G. Massuger, Marjanka J.J.M. Mingels, Yvette P. Geels |
| المصدر: | Human Pathology, 44, 10, pp. 2293-301 Human Pathology, 44, 2293-301 |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, medicine.medical_treatment, Aetiology, screening and detection [ONCOL 5], Comorbidity, Endometrium, Hysterectomy, Asymptomatic, Atypical hyperplasia, Pathology and Forensic Medicine, Translational research [ONCOL 3], Uterine Prolapse, medicine, Diabetes Mellitus, Humans, Vaginal bleeding, Prospective Studies, Prospective cohort study, Aged, Netherlands, Gynecology, Aged, 80 and over, Hereditary cancer and cancer-related syndromes [ONCOL 1], business.industry, Uterine prolapse, Hyperplasia, Middle Aged, medicine.disease, Aetiology, screening and detection Immune Regulation [ONCOL 5], Endometrial Neoplasms, Postmenopause, medicine.anatomical_structure, Premenopause, Endometrial Hyperplasia, Hypertension, Female, medicine.symptom, business |
| الوصف: | Contains fulltext : 143499.pdf (Publisher’s version ) (Closed access) Knowledge on the nature of the endometrium in women without symptoms of endometrial disease is poor. Therefore, the aim of this prospective study was to describe the endometrium of a cohort of asymptomatic women. The entire endometrium of premenopausal and postmenopausal women was embedded for histologic examination. All included patients underwent a hysterectomy on indication of uterovaginal prolapse, from July 2011 to October 2012, in 3 hospitals in the South of the Netherlands. Exclusion criteria were symptoms of postmenopausal vaginal blood loss or premenopausal disordered vaginal bleeding. As a result, 68 women were included in the study, 48 women were postmenopausal and 20 were premenopausal. In the endometrium of 10 women, simple hyperplasia was found (15%); 1, complex hyperplasia (2%); 2, simple atypical hyperplasia (3%); 2, complex atypical hyperplasia (3%); and 2, a small focus of intramucosal endometrioid endometrial carcinoma (3%). In general, the endometrium was heterogeneous, and most lesions were not present in the entire endometrium. In conclusion, after examining the entire endometrium, a remarkable high prevalence of endometrial pathology was found in asymptomatic women. The clinical meaning of these lesions is not yet clear, but endometrial pathology may frequently exist without symptoms. |
| وصف الملف: | application/pdf |
| تدمد: | 0046-8177 |
| DOI: | 10.1016/j.humpath.2013.05.011 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2b3d6c3578125f0ef4acbe1e4289c0 https://doi.org/10.1016/j.humpath.2013.05.011 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bf2b3d6c3578125f0ef4acbe1e4289c0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00468177 |
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| DOI: | 10.1016/j.humpath.2013.05.011 |