أعرض في EDS

Clinical Course and Outcome in Children with Congenital Hyperinsulinism

التفاصيل البيبلوغرافية
العنوان: Clinical Course and Outcome in Children with Congenital Hyperinsulinism
المؤلفون: Hedyeh Saneifard, Elham Hajihashemi, Minoo Fallahi
المصدر: Archives of Iranian Medicine. 25:422-427
بيانات النشر: Maad Rayan Publishing Company, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Hydrocortisone, Infant, Newborn, Humans, Congenital Hyperinsulinism, General Medicine, Child, Infant, Newborn, Diseases
الوصف: Background: Hyperinsulinism is the most common cause of persistent or recurrent neonatal hypoglycemia that may result in neurological deficits. The treatment goal in these patients is prevention of hypoglycemia to decrease mortality and morbidity. This study was done to determine the clinical course and outcome in children with congenital hyperinsulinism (CHI) referring to Mofid Children’s Hospital from 2011 to 2017. Methods: This study was done on 22 children with CHI referring to Mofid Children’s Hospital from 2011 to 2017. The demographic, perinatal, clinical, laboratory, imaging, pharmacological, treatment and follow up data of these children were collected and analyzed. Results: Among 22 children with CHI, the mortality rate was higher among those who received hydrocortisone versus those who did not receive hydrocortisone (46% versus 40%). Conclusion: According to the results of this study, hydrocortisone had a negative impact on the outcomes of these children, which is important in the management of hypoglycemia. The clinical course and outcome of children with CHI was better with medical compared to surgical treatment.
تدمد: 1735-3947
1029-2977
DOI: 10.34172/aim.2022.70
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf03d8be30b85f8c196fba4edccc2b01
https://doi.org/10.34172/aim.2022.70
رقم الانضمام: edsair.doi.dedup.....bf03d8be30b85f8c196fba4edccc2b01
قاعدة البيانات: OpenAIRE
الوصف
تدمد:17353947
10292977
DOI:10.34172/aim.2022.70