Stent placement for benign esophageal leaks, perforations, and fistulae: a clinical prediction rule for successful leakage control
| العنوان: | Stent placement for benign esophageal leaks, perforations, and fistulae: a clinical prediction rule for successful leakage control |
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| المؤلفون: | Wouter F.W. Kappelle, Mark I. van Berge Henegouwen, Robert Lindeboom, Manon C.W. Spaander, Jeanin E. van Hooft, Emo E. van Halsema, Frank P. Vleggaar, Paul Fockens, Bas L. Weusten |
| المساهمون: | Graduate School, Gastroenterology and Hepatology, Master Evidence Based Practice, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Surgery, Gastroenterology & Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism |
| المصدر: | Endoscopy, 50(2), 98-108. Georg Thieme Verlag Endoscopy, 50(2), 98. Georg Thieme Verlag |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Leak, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Esophagus/diagnostic imaging, Anastomotic Leak, Clinical prediction rule, 030230 surgery, Endoscopy, Gastrointestinal, 03 medical and health sciences, Esophageal Fistula, 0302 clinical medicine, Esophagus, Esophageal Fistula/diagnosis, medicine, Journal Article, Humans, Derivation, Tomography, Retrospective Studies, Esophageal Perforation, medicine.diagnostic_test, business.industry, Gastrointestinal/methods, Gastroenterology, Stent, Endoscopy, Retrospective cohort study, Endoscopy, Gastrointestinal/methods, Middle Aged, X-Ray Computed, Surgery, Multicenter Study, medicine.anatomical_structure, 030211 gastroenterology & hepatology, Anastomotic Leak/diagnosis, Female, Stents, Esophageal Perforation/diagnosis, business, Tomography, X-Ray Computed, Follow-Up Studies |
| الوصف: | Background and study aims Sealing esophageal leaks by stent placement allows healing in 44 % – 94 % of patients. We aimed to develop a prediction rule to predict the chance of successful stent therapy. Patients and methods In this multicenter retrospective cohort study, patients with benign upper gastrointestinal leakage treated with stent placement were included. We used logistic regression analysis including four known clinical predictors of stent therapy outcome. The model performance to predict successful stent therapy was evaluated in an independent validation sample. Results We included etiology, location, C-reactive protein, and size of the leak as clinical predictors. The model was estimated from 145 patients (derivation sample), and 59 patients were included in the validation sample. Stent therapy was successful in 55.9 % and 67.8 % of cases, respectively. The predicted probability of successful stent therapy was significantly higher in success patients compared with failure patients in both the derivation (P Conclusions This prediction rule, consisting of four clinical predictors, could identify patients with esophageal leaks who were likely to benefit from or fail on stent therapy. The prediction rule can support clinical decision-making when the predicted probability of success is ≥ 70 % or ≤ 50 %. |
| وصف الملف: | image/pdf |
| اللغة: | English |
| تدمد: | 0013-726X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0cdf4acf88cc07c62ad36a404e132a https://pure.amc.nl/en/publications/stent-placement-for-benign-esophageal-leaks-perforations-and-fistulae-a-clinical-prediction-rule-for-successful-leakage-control(bb7d7b0f-4669-4aec-82fa-1356b7282d1f).html |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bd0cdf4acf88cc07c62ad36a404e132a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 0013726X |
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