Review of carcinogenicity of hexavalent chrome and proposal of revising approval standards for an occupational cancers in Korea
| العنوان: | Review of carcinogenicity of hexavalent chrome and proposal of revising approval standards for an occupational cancers in Korea |
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| المؤلفون: | Dae Hwan Kim, Sangyun Seo, Jungwon Kim, Yangho Kim |
| المصدر: | Annals of Occupational and Environmental Medicine Annals of Occupational and Environmental Medicine, Vol 30, Iss 1, Pp 1-5 (2018) |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, Occupational disease, Cumulative Exposure, Hexavalent chromium, Occupational safety and health, 03 medical and health sciences, 0302 clinical medicine, Disease registry, Environmental health, medicine, otorhinolaryngologic diseases, Lung cancer, Carcinogen, Cancer, business.industry, Public health, Public Health, Environmental and Occupational Health, Occupational exposure, medicine.disease, 030210 environmental & occupational health, Industrial medicine. Industrial hygiene, Lung neoplasm, RC963-969, Public aspects of medicine, RA1-1270, business, 030217 neurology & neurosurgery, Research Article |
| الوصف: | Background The objective of this study is to suggest revised recognition standards for occupational disease due to chromium (VI) by reflecting recent domestic and international research works and considering domestic exposure status with respect to target organs, exposure period, and cumulative exposure dose in relation to the chromium (VI)-induced occupational disease compensation. Methods In this study, the reports published by major international institutions such as World Health Organization (WHO) International Agency for Research on Cancer (IARC) (2012), Occupational Safety and Health Administration (OSHA) (2006), National Institute for Occupational Safety and Health (NIOSH) (2013), American Conference of Governmental Industrial Hygienists (ACGIH) (2004), National Toxicology Program (NTP) (2014), and Agency for Toxic Substances and Disease Registry (ASTDR) (2012) were reviewed and the recent research works searched by PubMed were summarized. Results Considering the recent research works and the domestic situation, only lung cancer is conserved in the legislative bill in relation to chromium (VI), and the exposure period is not included in the bill. Nasal and paranasal sinus cancer was excluded from the list of cancers that are compensated as the chromium (VI)- induced occupational disease, while lung cancer remains in the list. In the view of legislative unity, considering the fact that only the cancers having sufficient evidence are included in the conventional list of cancers compensated as occupational disease, nasal and paranasal sinus cancer having limited evidence were excluded from the list. The exposure period was also removed from the legislative bill due to the insufficient evidence. Recent advices in connection with cumulative exposure dose were proposed, and other considerable points were provided with respect to individual occupational relevance. Conclusions It is suggested that the current recognition standard which is “Lung cancer or nasal and paranasal sinus cancer caused by exposure to chromium (VI) or compounds thereof (exposure for two years or longer), or nickel compounds” should be changed to “Lung cancer caused by exposure to chromium (VI) or compounds thereof, and lung cancer or nasal and paranasal sinus cancer caused by exposure to nickel compounds”. |
| تدمد: | 2052-4374 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcea673145378645d96c94834e4b2b20 https://pubmed.ncbi.nlm.nih.gov/29423230 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bcea673145378645d96c94834e4b2b20 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20524374 |
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