THE EXPERIMENTAL STUDY OF STRESS-RELATED PATHOLOGICAL CHANGES IN CEREBRAL VENOUS BLOOD FLOW IN NEWBORN RATS ASSESSED BY DOCT
| العنوان: | THE EXPERIMENTAL STUDY OF STRESS-RELATED PATHOLOGICAL CHANGES IN CEREBRAL VENOUS BLOOD FLOW IN NEWBORN RATS ASSESSED BY DOCT |
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| المؤلفون: | Valery V. Tuchin, Ekaterina Zinchenko, Vladislav V. Lychagov, Mohhanad M. Kassim, Olga Bibikova, Al-Fatle Fatema Ali, Oxana Semyachkina-Glushkovskaya, Maria V. Ulanova, S. S. Sindeev, Igor A. Semyachkin-Glushkovskiy, Al Hassani Leith |
| المصدر: | Journal of Innovative Optical Health Sciences, Vol 6, Iss 3, Pp 1350023-1-1350023-10 (2013) |
| بيانات النشر: | World Scientific Pub Co Pte Ltd, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | stress-related intracranial hemorrhage, adrenaline, lcsh:T, business.industry, cerebral venous blood flow, Biomedical Engineering, Medicine (miscellaneous), Hemodynamics, Venous blood, lcsh:Technology, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, medicine.anatomical_structure, Doppler optical coherence tomography, Anesthesia, Venous blood flow, lcsh:QC350-467, Medicine, business, Vein, Pathological, lcsh:Optics. Light |
| الوصف: | In experiments on newborn rats with stress-related intracranial hemorrhage (ICH) using Doppler optical coherence tomography (DOCT) we have shown that latent stage of ICH (4 h after stress) is characterized by decrease of venous blood outflow and the loss of sensitivity of sagittal vein to vasoconstrictor effect of adrenaline. The incidence of ICH (24 h after stress) was accompanied by progression of early pathological changes in cerebral venous blood flow (CVBF) and development of venous insufficiency. Taking into consideration of this fact, we suggest that the suppression of CVBF related to the severity to the deleterious effect of stress on the brain hemodynamics in newborn rats. These facts allow us to conclude that the venous insufficiency with the loss of vasoconstrictor response to adrenaline is an informative and sensitive component of pattern of CVBF that can be important diagnostic criteria of risk of ICH development in newborns. |
| تدمد: | 1793-7205 1793-5458 |
| DOI: | 10.1142/s1793545813500235 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2a1f358c967c0449db31f5e51c30be https://doi.org/10.1142/s1793545813500235 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....bc2a1f358c967c0449db31f5e51c30be |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17937205 17935458 |
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| DOI: | 10.1142/s1793545813500235 |