The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study
| العنوان: | The landscape for HIV pre-exposure prophylaxis during pregnancy and breastfeeding in Malawi and Zambia: A qualitative study |
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| المؤلفون: | Benjamin H. Chi, Oliver Mweemba, Twambilile Phanga, Tulani Francis L. Matenga, Kellie Freeborn, Wilbroad Mutale, Nora E. Rosenberg, Wezzie Dunda, Kasapo F Chibwe, Leah Schrubbe, Suzanne Maman, Chifundo Zimba, Bellington Vwalika |
| المصدر: | PLoS ONE, Vol 14, Iss 10, p e0223487 (2019) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | RNA viruses, 0301 basic medicine, Malawi, Epidemiology, Maternal Health, Breastfeeding, HIV Infections, Pathology and Laboratory Medicine, Pediatrics, Geographical Locations, Pre-exposure prophylaxis, 0302 clinical medicine, Immunodeficiency Viruses, Pregnancy, Health care, Medicine and Health Sciences, Medicine, 030212 general & internal medicine, Pregnancy Complications, Infectious, Qualitative Research, Multidisciplinary, Obstetrics and Gynecology, 3. Good health, Outreach, Breast Feeding, Medical Microbiology, HIV epidemiology, Viral Pathogens, Viruses, Female, Pathogens, Research Article, Adult, medicine.medical_specialty, Anti-HIV Agents, Science, HIV prevention, Zambia, Microbiology, Young Adult, 03 medical and health sciences, Retroviruses, Humans, Microbial Pathogens, Preventive medicine, Prophylaxis, business.industry, Public health, Lentivirus, Organisms, Biology and Life Sciences, HIV, medicine.disease, 030112 virology, Public and occupational health, Family medicine, People and Places, Africa, Women's Health, Pre-Exposure Prophylaxis, Neonatology, business, Breast feeding, Qualitative research |
| الوصف: | High HIV incidence rates have been observed among pregnant and breastfeeding women in sub-Saharan Africa. Oral pre-exposure prophylaxis (PrEP) can effectively reduce HIV acquisition in women during these periods; however, understanding of its acceptability and feasibility in antenatal and postpartum populations remains limited. To address this gap, we conducted in-depth interviews with 90 study participants in Malawi and Zambia: 39 HIV-negative pregnant/breastfeeding women, 14 male partners, 19 healthcare workers, and 18 policymakers. Inductive and deductive approaches were used to identify themes related to PrEP. As a public health intervention, PrEP was not well-known among patients and healthcare workers; however, when it was described to participants, most expressed positive views. Concerns about safety and adherence were raised, highlighting two critical areas for community outreach. The feasibility of introducing PrEP into antenatal services was also a concern, especially if introduced within already strained health systems. Support for PrEP varied among policymakers in Malawi and Zambia, reflecting the ongoing policy discussions in their respective countries. Implementing PrEP during the pregnancy and breastfeeding periods will require addressing barriers at the individual, facility, and policy levels. Multi- level approaches should be considered in the design of new PrEP programs for antenatal and postpartum populations. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b819387244159712aead831ab9d6aadc https://doaj.org/article/58bc10b2f1a240aeb570fc70834369e3 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b819387244159712aead831ab9d6aadc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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