Microbial and host‐derived biomarker changes during ligature‐induced and spontaneous peri‐implantitis in the Beagle dog
| العنوان: | Microbial and host‐derived biomarker changes during ligature‐induced and spontaneous peri‐implantitis in the Beagle dog |
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| المؤلفون: | Daniel Buser, Alberto Monje, Sigrun Eick, Giovanni E. Salvi |
| المصدر: | Journal of Periodontal Research. 56:93-100 |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Peri-implantitis, medicine.medical_treatment, Bacterial counts, Gastroenterology, Beagle, 03 medical and health sciences, Dogs, 0302 clinical medicine, Internal medicine, medicine, Animals, Tannerella forsythia, Ligature, Dental Implants, biology, business.industry, Disease progression, Prevotella intermedia, 030206 dentistry, biology.organism_classification, Peri-Implantitis, Bacterial Load, 030104 developmental biology, Periodontics, Biomarker (medicine), business, Biomarkers |
| الوصف: | OBJECTIVE To evaluate microbial and host-derived biomarker changes during experimental peri-implantitis in the Beagle dog. BACKGROUND Limited data exist on the microbial and biomarker changes during progressive bone loss as result of experimental peri-implantitis. METHODS In total, 36 implants (ndogs = 6) were assessed over 3 episodes of ligature-induced peri-implantitis followed by a period of spontaneous progression. Implants with hybrid (H) and completely rough (R) surface designs were used. Clinical and radiographic parameters were recorded at 4 timepoints. Peri-implant sulcus fluid was collected from the buccal and lingual aspects of the implants. The presence of 7 bacterial species and 2 host-derived biomarkers was assessed during the study period. RESULTS Total bacterial counts were significantly correlated with marginal bone loss (MBL) (r = .21; P = .009). Further, Phorphyromonas gulae (Pg) and Tannerella forsythia (Tf) were commonly correlated with MBL, suppuration (SUP) and the sulcular bleeding index scores (mSBI) (P |
| تدمد: | 1600-0765 0022-3484 |
| DOI: | 10.1111/jre.12797 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cce6c11b0af6a2ea5e728ab73bc166 https://doi.org/10.1111/jre.12797 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....b7cce6c11b0af6a2ea5e728ab73bc166 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16000765 00223484 |
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| DOI: | 10.1111/jre.12797 |