Dynamics of Pneumocystis carinii Air Shedding During Experimental Pneumocystosis
| العنوان: | Dynamics of Pneumocystis carinii Air Shedding During Experimental Pneumocystosis |
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| المؤلفون: | Nausicaa Gantois, Jean Menotti, Anne Totet, Yves J. F. Garin, Francis Derouin, Eduardo Dei-Cas, El Moukhtar Aliouat, Firas Choukri, Vance Bergeron |
| المصدر: | The Journal of Infectious Diseases. 203:1333-1336 |
| بيانات النشر: | Oxford University Press (OUP), 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Time Factors, Air Microbiology, Mycology, Biology, Pneumocystis carinii, Polymerase Chain Reaction, law.invention, law, Pneumocystosis, medicine, Animals, Immunology and Allergy, DNA, Fungal, Lung, Mycosis, Polymerase chain reaction, Pneumonia, Pneumocystis, Respiratory disease, medicine.disease, Exhaled air, Lung involvement, Virology, Rats, respiratory tract diseases, Disease Models, Animal, Infectious Diseases, medicine.anatomical_structure |
| الوصف: | To better understand the diffusion of Pneumocystis in the environment, airborne shedding of Pneumocystis carinii in the surrounding air of experimentally infected rats was quantified by means of a real-time polymerase chain reaction assay, in parallel with the kinetics of P. carinii loads in their lungs. P. carinii DNA was detected in the air 1 week after infection and increased until 4-5 weeks after infection before stabilizing. A significant correlation was shown between lung burdens and the corresponding airborne levels, suggesting the possibility of estimating the fungal lung involvement through quantification of Pneumocystis in the exhaled air. |
| تدمد: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/jir018 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b659747b583410649e502b1f78d798c4 https://doi.org/10.1093/infdis/jir018 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b659747b583410649e502b1f78d798c4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15376613 00221899 |
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| DOI: | 10.1093/infdis/jir018 |