MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells
| العنوان: | MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells |
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| المؤلفون: | Thomas Bein, Johannes Sicklinger, Tobias Preiß, Simone Braig, Joachim O. Rädler, Angelika M. Vollmar, Andreas Zimpel, Stefan Wuttke, Claudia Bellomo |
| المصدر: | Chemical Communications. 51:15752-15755 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Chromium, Lipid Bilayers, Nanoparticle, Nanotechnology, Ferric Compounds, Catalysis, Cell Line, Tumor, Organometallic Compounds, Materials Chemistry, Humans, Lipid bilayer, Fluorescent Dyes, Drug Carriers, Chemistry, fungi, Metals and Alloys, General Chemistry, Glycerylphosphorylcholine, Porous scaffold, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Drug delivery, Cancer cell, Phosphatidylcholines, Ceramics and Composites, Nanoparticles, Fluorescein, lipids (amino acids, peptides, and proteins), Nanocarriers, Drug carrier, Porosity |
| الوصف: | We report the synthesis of MOF@lipid nanoparticles as a versatile and powerful novel class of nanocarriers based on metal-organic frameworks (MOFs). We show that the MOF@lipid system can effectively store dye molecules inside the porous scaffold of the MOF while the lipid bilayer prevents their premature release. Efficient uptake of the MOF@lipid nanoparticles by cancer cells makes these nanocarriers promising for drug delivery and diagnostic purposes. |
| تدمد: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c5cc06767g |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cbcd291c48bd052f9d4606f35aa7c9 https://doi.org/10.1039/c5cc06767g |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b5cbcd291c48bd052f9d4606f35aa7c9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1364548X 13597345 |
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| DOI: | 10.1039/c5cc06767g |