Controlling the kinetic chain length of the crosslinks in photo-polymerized biodegradable networks
| العنوان: | Controlling the kinetic chain length of the crosslinks in photo-polymerized biodegradable networks |
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| المؤلفون: | Jan Feijen, George Mihov, Dirk W. Grijpma, Janine Jansen, Thomas N. S. van der Horst, Sjoerd van der Wal, Abdul Ghaffar |
| المساهمون: | W.J. Kolff Institute for Biomedical Engineering and Materials Science (KOLFF), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Analytical Chemistry and Forensic Science (HIMS, FNWI), Faculty of Science and Technology, Biomaterials Science and Technology |
| المصدر: | Journal of Materials Science-Materials in Medicine, 24(4), 877-888. SPRINGER Journal of Materials Science-Materials in Medicine, 24(4), 877-888. Springer Netherlands Journal of Materials Science: Materials in Medicine, 24(4), 877-888. Springer |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Kinetic chain length, CYTOCOMPATIBILITY, Materials science, POLY(ETHYLENE GLYCOL), Polymers, Radical polymerization, HYDROGELS, Biomedical Engineering, Biophysics, CHROMATOGRAPHY, Bioengineering, Biocompatible Materials, MONOMERS, ESTER, Methacrylate, chemistry.chemical_compound, PMAA, Kinetic chain, Polymer chemistry, Urethane acrylate, BIOMATERIALS, Mercaptoethanol, DEGRADATION, Photochemical Processes, Biodegradable polymer, Crosslink density, METIS-302413, Methacrylic acid, UV, Kinetics, Monomer, IR-90184, chemistry, Polymerization, Living polymerization, BEHAVIOR |
| الوصف: | Biodegradable polymer networks were prepared by photo-initiated radical polymerization of methacrylate functionalized poly(D, L-lactide) oligomers. The kinetic chains formed in this radical polymerization are the multifunctional crosslinks of the networks. These chains are carbon-carbon chains that remain after degradation. If their molecular weight is too high these poly(methacrylic acid) chains can not be excreted by the kidneys. The effect of the photo-initiator concentration and the addition of 2-mercaptoethanol as a chain transfer agent on the molecular weight of the kinetic chains was investigated. It was found that both increasing the initiator concentration and adding 2-mercaptoethanol decrease the kinetic chain length. However, the effect of adding 2-mercaptoethanol was much larger. Some network properties such as the glass transition temperature and the swelling ratio in acetone are affected when the kinetic chain length is decreased. |
| تدمد: | 1573-4838 0957-4530 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae56119c103cdd4ebcdd734322e28a46 https://pubmed.ncbi.nlm.nih.gov/23371770 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ae56119c103cdd4ebcdd734322e28a46 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15734838 09574530 |
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