A 11‐Steps Total Synthesis of Magellanine through a Gold(I)‐Catalyzed Dehydro Diels–Alder Reaction
| العنوان: | A 11‐Steps Total Synthesis of Magellanine through a Gold(I)‐Catalyzed Dehydro Diels–Alder Reaction |
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| المؤلفون: | Louis Barriault, Philippe McGee, Geneviève Bétournay, Francis Barabé |
| المصدر: | Angewandte Chemie International Edition. 56:6280-6283 |
| بيانات النشر: | Wiley, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 010405 organic chemistry, Chemistry, Total synthesis, General Medicine, General Chemistry, 010402 general chemistry, 01 natural sciences, Catalysis, Cycloaddition, 0104 chemical sciences, chemistry.chemical_compound, Rapid access, Organic chemistry, Magellanine, Diels–Alder reaction |
| الوصف: | We have developed an innovative strategy for the formation of angular carbocycles via a gold(I)-catalyzed dehydro Diels-Alder reaction. This transformation provides rapid access to a variety of complex angular cores in excellent diastereoselectivities and high yields. The usefulness of this AuI -catalyzed cycloaddition was further demonstrated by accomplishing a 11-steps total synthesis of (±)-magellanine. |
| تدمد: | 1521-3773 1433-7851 |
| DOI: | 10.1002/anie.201611606 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4c86c2b32966f87ade22faba11a960 https://doi.org/10.1002/anie.201611606 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....ad4c86c2b32966f87ade22faba11a960 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15213773 14337851 |
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| DOI: | 10.1002/anie.201611606 |