Successive immunoglobulin and cytokine expression in the small intestine of juvenile chicken
| العنوان: | Successive immunoglobulin and cytokine expression in the small intestine of juvenile chicken |
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| المؤلفون: | Arne Jansma, Henk K. Parmentier, Willemien H. Wieland, Trudy Straetemans, Gerco den Hartog, Arjen Schots, Aart Lammers, L. Kruijt |
| المصدر: | Developmental and Comparative Immunology 34 (2010) 12 Developmental and Comparative Immunology, 34(12), 1254-1262 |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Immunoglobulin A, mucosal surfaces, Gene Expression, Polymerase Chain Reaction, Jejunum, Intestinal mucosa, Gene expression, Intestine, Small, transcriptional regulation, Intestinal Mucosa, biology, Genes, Immunoglobulin, EPS-2, Receptors, Polymeric Immunoglobulin, polymeric ig receptor, medicine.anatomical_structure, Adaptation Physiology, Cytokines, Antibody, medicine.medical_specialty, Immunology, Immunoglobulins, Ileum, Celbiologie en Immunologie, Internal medicine, medicine, Animals, RNA, Messenger, Adaptatiefysiologie, Laboratorium voor Nematologie, Immunity, Mucosal, commensal bacteria, Research, Interleukins, Small intestine, promoter elements, Endocrinology, Cell Biology and Immunology, secretory iga, Immunoglobulin M, transport, Immunoglobulin A, Secretory, biology.protein, WIAS, cells, adaptive immune-responses, microflora, Interferons, Laboratory of Nematology, Polymeric immunoglobulin receptor, Chickens, Developmental Biology, Onderzoek |
| الوصف: | The intestinal mucosa is of major importance for immune development. To further study the ontogeny of avian mucosal immunity, mRNA levels of IgM, IgY and IgA, the polymeric immunoglobulin receptor (pIgR) and a number of cytokines were determined at different ages in jejunum and ileum of non-immunized healthy juvenile layer chickens. Immunoglobulin genes were successively expressed in jejunum and ileum. IgM expression was maximal in week 1, IgY expression peaked in week 5, and IgA expression was most dominant after week 7 post hatch. PIgR gene expression was relatively low in the first 2 weeks post hatch, but increased thereafter. Generally, increased expression levels of IL-1, IL-10, IL-12p40, iNOS and interferon-¿ mRNA levels were found between days 14–42 as compared to days 3 and 49–70 post hatch (p |
| وصف الملف: | application/pdf; application/octet-stream |
| تدمد: | 1879-0089 0145-305X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::accc411cbf4b3bce6e15f488d784b678 https://pubmed.ncbi.nlm.nih.gov/20621117 |
| Rights: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....accc411cbf4b3bce6e15f488d784b678 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18790089 0145305X |
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