A prospective epidemiological analysis of controlling nutritional status score with the poor functional outcomes in Chinese patients with haemorrhagic stroke
| العنوان: | A prospective epidemiological analysis of controlling nutritional status score with the poor functional outcomes in Chinese patients with haemorrhagic stroke |
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| المؤلفون: | Sheng Lie Ye, Man Man Zhang, Liang Wang, Bo Yang, Yan Zhi Wu, Cheng-wei Liao, Zhi Peng Liu, Bei Lei Zhu, Qun Li Lin, Zhong Ming Cai, Ren Qian Feng, Le Qiu Sun, Xue Rong Huang, Hao Man Chen, Xu Dong Zhou |
| المصدر: | British Journal of Nutrition. 128:192-199 |
| بيانات النشر: | Cambridge University Press (CUP), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Nutrition and Dietetics, business.industry, Medicine (miscellaneous), Clinical nutrition, Odds ratio, medicine.disease, Haemorrhagic stroke, Confidence interval, Malnutrition, Modified Rankin Scale, Internal medicine, Cohort, Epidemiology, medicine, business |
| الوصف: | Nutritional Risk Screening index is a standard tool to assess nutritional risk, but epidemiological data are scarce on controlling nutritional status (CONUT) as a prognostic marker in acute haemorrhagic stroke (AHS). We aimed to explore whether the CONUT may predict a 3-month functional outcome in AHS. In total, 349 Chinese patients with incident AHS were consecutively recruited, and their malnutrition risks were determined using a high CONUT score of ≥ 2. The cohort patients were divided into high-CONUT (≥ 2) and low-CONUT (< 2) groups, and primary outcomes were a poor functional prognosis defined as the modified Rankin Scale (mRS) score of ≥ 3 at post-discharge for 3 months. Odds ratios (OR) with 95 % confidence intervals (CI) for the poor functional prognosis at post-discharge were estimated by using a logistic analysis with additional adjustments for unbalanced variables between the high-CONUT and low-CONUT groups. A total of 328 patients (60·38 ± 12·83 years; 66·77 % male) completed the mRS assessment at post-discharge for 3 months, with 172 patients at malnutrition risk at admission and 104 patients with a poor prognosis. The levels of total cholesterol and total lymphocyte counts were significantly lower in high-CONUT patients than low-CONUT patients (P = 0·012 and < 0·001, respectively). At 3-month post discharge, there was a greater risk for the poor outcome in the high-CONUT compared with the low-CONUT patients at admission (OR: 2·32, 95 % CI: 1·28, 4·17). High-CONUT scores independently predict a 3-month poor prognosis in AHS, which helps to identify those who need additional nutritional managements. |
| تدمد: | 1475-2662 0007-1145 |
| DOI: | 10.1017/s0007114521003184 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d45d44bb81eaca30c31cec8b615d6d https://doi.org/10.1017/s0007114521003184 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....a6d45d44bb81eaca30c31cec8b615d6d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752662 00071145 |
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| DOI: | 10.1017/s0007114521003184 |