Appendicitis remains the most common surgical emergency in practice. Hem-O-Lok is frequently used in laparoscopic appendectomy for appendicular stump. Migration of Hem-O-Lok is a rare complication with only a few case reports. We present a case with migration of Hem-O-Lok to fallopian tube after laparoscopic appendectomy and causes tubal-ovarian abscess. Surgeons and gynecologists should put this diagnosis in mind when patient complaints of right lower abdominal pain after laparoscopic procedure.