Assessment of left ventricular function in horses with aortic regurgitation by 2D speckle tracking
| العنوان: | Assessment of left ventricular function in horses with aortic regurgitation by 2D speckle tracking |
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| المؤلفون: | Dominique De Clercq, F. Rademakers, G. van Loon, Annelies Decloedt, S. Ven |
| المصدر: | BMC Veterinary Research BMC Veterinary Research, Vol 16, Iss 1, Pp 1-9 (2020) BMC VETERINARY RESEARCH |
| بيانات النشر: | BioMed Central, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, 040301 veterinary sciences, Aortic Valve Insufficiency, Diastole, Strain (injury), HEALTHY HORSES, Regurgitation (circulation), 030204 cardiovascular system & hematology, Valvular regurgitation, Ventricular Function, Left, Strain, 0403 veterinary science, 03 medical and health sciences, AGE, 0302 clinical medicine, Internal medicine, 2d speckle tracking, MANAGEMENT, medicine, Animals, Veterinary Sciences, Interventricular septum, Horses, DISPLACEMENT, STRAIN-RATE, lcsh:Veterinary medicine, General Veterinary, Ventricular function, business.industry, Strain rate, 04 agricultural and veterinary sciences, General Medicine, MYOCARDIAL DEFORMATION, QUANTIFICATION, medicine.disease, WALL-MOTION, Warmblood, medicine.anatomical_structure, Cross-Sectional Studies, Echocardiography, Heart failure, Case-Control Studies, Cardiology, lcsh:SF600-1100, Female, Horse Diseases, business, Research Article |
| الوصف: | Background Aortic regurgitation (AR) may lead to left ventricular (LV) dilatation, cardiac arrhythmias and heart failure. Close follow-up of horses with AR is therefore paramount to detect onset of cardiac decompensation. The aim of this study was to examine whether two-dimensional speckle tracking (2DST) can be used to detect altered myocardial function in horses with chronic AR compared to control horses. Speckle tracking was performed on short axis and long axis images of the LV in 29 healthy Warmblood horses and 57 Warmblood horses with AR. Radial, circumferential and longitudinal strain, strain rate and displacement were measured for each segment separately and the average was calculated over all segments. Data generated from the apical segments were not included in the analysis. Results Radial (SR) and circumferential (SC) strain were significantly higher in horses with moderate AR (average SR 75.5 ± 24.3%, SC 19.3 ± 3.2%) but not in horses with severe AR (SR 65.5 ± 26.2%, SC 16.3 ± 3.5%), compared to control horses (SR 54.5 ± 18.0%, SC 16.8 ± 3.0%). Longitudinal strain did not show significant differences, but longitudinal displacement (DL) was larger in horses with moderate (average DL 29.5 ± 4.1 cm) and severe AR (DL 32.4 ± 6.1 cm) compared to control horses (DL 25.7 ± 4.0 cm), especially in the interventricular septum. Diastolic longitudinal strain rate was lower in early diastole in horses with severe AR (0.93 ± 0.18/s) compared to controls (1.13 ± 0.13/s). Conclusions 2DST is able to detect altered myocardial motion in horses with AR, which showed significantly higher radial and circumferential strain. Further research is needed to determine whether these findings contribute to a more accurate diagnosis and prognosis in clinical cases. |
| وصف الملف: | Electronic; application/pdf |
| اللغة: | English |
| تدمد: | 1746-6148 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4be8069d8e0ed404c304d320249f2a6 http://europepmc.org/articles/PMC7085189 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a4be8069d8e0ed404c304d320249f2a6 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17466148 |
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