Isoprenylated xanthones and flavonoids from Cudrania tricuspidata
العنوان: | Isoprenylated xanthones and flavonoids from Cudrania tricuspidata |
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المؤلفون: | Guo-Fu Zhu, Ai-Jun Hou, Ying-Shu Zou |
المصدر: | Chemistrybiodiversity. 2(1) |
سنة النشر: | 2006 |
مصطلحات موضوعية: | Stereochemistry, Xanthones, Bioengineering, Biochemistry, Moraceae, Plant Roots, chemistry.chemical_compound, Inhibitory Concentration 50, Cell Line, Tumor, Xanthone, Ic50 values, Cudrania tricuspidata, Humans, Molecular Biology, Flavonoids, biology, Molecular Structure, Cudraflavone C, Macluraxanthone B, General Chemistry, General Medicine, biology.organism_classification, Antineoplastic Agents, Phytogenic, Macluraxanthone C, chemistry, Phytochemical, Molecular Medicine |
الوصف: | Further phytochemical investigation on the roots of Cudrania tricuspidata afforded a new isoprenylated xanthone, cudratricusxanthone I (1), two new isoprenylated flavanones, cudraflavanones C and D (2 and 3, resp.), and seven known compounds, 1,7-dihydroxy-3,6-dimethoxyxanthone (4), macluraxanthone C (5), cudraxanthones E, K, and L (6, 7, and 8, resp.), cudraflavanone A (9), and cudraflavone C (10). Their structures were identified by spectroscopic methods. Cudratricusxanthone H (12), macluraxanthone B (13), two xanthones previously isolated from this plant, and 5, showed significant inhibitory effects on four kinds of human digestive apparatus tumor cell lines (HCT-116, SMMC-7721, SGC-7901, and BGC-823) with IC50 values of 2.70-12.66 microM. |
تدمد: | 1612-1880 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d8268bbda4cff6359124a93cafae1d https://pubmed.ncbi.nlm.nih.gov/17191926 |
Rights: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....a1d8268bbda4cff6359124a93cafae1d |
قاعدة البيانات: | OpenAIRE |
تدمد: | 16121880 |
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