Isoprenylated xanthones and flavonoids from Cudrania tricuspidata

التفاصيل البيبلوغرافية
العنوان: Isoprenylated xanthones and flavonoids from Cudrania tricuspidata
المؤلفون: Guo-Fu Zhu, Ai-Jun Hou, Ying-Shu Zou
المصدر: Chemistrybiodiversity. 2(1)
سنة النشر: 2006
مصطلحات موضوعية: Stereochemistry, Xanthones, Bioengineering, Biochemistry, Moraceae, Plant Roots, chemistry.chemical_compound, Inhibitory Concentration 50, Cell Line, Tumor, Xanthone, Ic50 values, Cudrania tricuspidata, Humans, Molecular Biology, Flavonoids, biology, Molecular Structure, Cudraflavone C, Macluraxanthone B, General Chemistry, General Medicine, biology.organism_classification, Antineoplastic Agents, Phytogenic, Macluraxanthone C, chemistry, Phytochemical, Molecular Medicine
الوصف: Further phytochemical investigation on the roots of Cudrania tricuspidata afforded a new isoprenylated xanthone, cudratricusxanthone I (1), two new isoprenylated flavanones, cudraflavanones C and D (2 and 3, resp.), and seven known compounds, 1,7-dihydroxy-3,6-dimethoxyxanthone (4), macluraxanthone C (5), cudraxanthones E, K, and L (6, 7, and 8, resp.), cudraflavanone A (9), and cudraflavone C (10). Their structures were identified by spectroscopic methods. Cudratricusxanthone H (12), macluraxanthone B (13), two xanthones previously isolated from this plant, and 5, showed significant inhibitory effects on four kinds of human digestive apparatus tumor cell lines (HCT-116, SMMC-7721, SGC-7901, and BGC-823) with IC50 values of 2.70-12.66 microM.
تدمد: 1612-1880
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d8268bbda4cff6359124a93cafae1d
https://pubmed.ncbi.nlm.nih.gov/17191926
Rights: CLOSED
رقم الانضمام: edsair.doi.dedup.....a1d8268bbda4cff6359124a93cafae1d
قاعدة البيانات: OpenAIRE